Generated by All in One SEO v5.0.1.1, this is an llms.txt file, used by LLMs to index the site. # Banting Research Foundation The first health science discovery catalyst in Canada ## Sitemaps - [XML Sitemap](https://www.bantingdiscoveryfoundation.ca/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [News](https://www.bantingdiscoveryfoundation.ca/blog/) - [Banting Discovery Foundation 2026 Award Winners](https://www.bantingdiscoveryfoundation.ca/banting-discovery-foundation-2026-award-winners-newsletter/) - Toronto, June 16, 2026 - The Banting Discovery Foundation is pleased to announce this year’s Discovery Award winners: Michael Colacci (Department of Medicine, University of Toronto), received the Banting 100-Year Social Impact Award – supported by the generous donations of past Discovery Award recipients with matched gifts from The Madison Foundation – for his collaborative - [The Banting Discovery Foundation Announces its 100th Cohort of Award Winners](https://www.bantingdiscoveryfoundation.ca/the-banting-discovery-foundation-announces-its-100th-cohort-of-award-winners/) - Banting Discovery FoundationToronto, Ontario – Founded in 1925, the Banting Discovery Foundation is pleased to announce its 100th cohort of Discovery Award recipients. In addition to our returning partners, the Ontario Brain Institute and the Heaslip Foundation, we would also like to thank our new funding partners, namely the Canerector Foundation, and the Novo Nordisk - [The Now-Renamed Banting Discovery Foundation Announces its 99th Cohort of Award Winners](https://www.bantingdiscoveryfoundation.ca/the-now-renamed-banting-discovery-foundation-announces-its-99th-cohort-of-award-winners/) - Toronto, Ontario – As Canada’s first grant-giving charity in biomedical and health research, the Banting Discovery Foundation has announced the eight latest Discovery Award winners. The early-career scientists will each receive up to $30,000 to pursue their moonshot research projects. Our Discovery Awardees are rooted in disciplines ranging from basic science to public health to - [Unveiling Our 2024 Case for Support](https://www.bantingdiscoveryfoundation.ca/2024-case-for-support/) - As we step into a new year, we are excited to unveil our 2024 Case for Support, a comprehensive document that outlines our ambitious goals, the challenges we aim to tackle, and the impact we strive to make. This year, we're not just asking for support; we're inviting you to join us in a movement for change. - [ReDiscovery of the Banting Legacy: Nov 6 Virtual Panel Discussion](https://www.bantingdiscoveryfoundation.ca/rediscovery-of-the-banting-legacy-a-century-of-biomedical-discovery-and-innovation/) - Join the Banting Research Foundation in celebrating 100 years of biomedical Discovery granting. Learn about the legacy of Dr. Frederick Banting and the impact of the Foundation's work on health and wellness. - [Banting Discovery Awardee, Dr. Robert Huber: Unraveling the Enigma of Batten Disease](https://www.bantingdiscoveryfoundation.ca/banting-discovery-awardee-dr-robert-huber-unraveling-the-enigma-of-batten-disease/) - Delve into the groundbreaking research of Banting Discovery Awardee, Dr. Robert Huber, as he navigates the complexities of Batten disease. Through innovative methods and heartfelt commitment, Dr. Huber illuminates a path toward understanding and potential treatments. - [Master the Art of Grant Writing: 13 Essential Tips From an Insider](https://www.bantingdiscoveryfoundation.ca/master-the-art-of-grant-writing-13-essential-tips-from-an-insider/) - Looking to ace your next grant application? This blog post offers a definitive guide to grant writing, featuring a 13-step checklist from Mireille Consalvey, an expert in the field. Discover actionable tips and insights to elevate your grant writing skills and boost your chances of success. - [2023 Discovery Awardee: Sergio Crespo-Garcia](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-sergio-crespo-garcia/) - Sergio Crespo-Garcia, PhD, is a highly accomplished Assistant Professor who has made significant contributions to the field of retinal degeneration research. With his extensive expertise and diverse academic background, he continues to push the boundaries of knowledge in his quest to understand and treat age-related macular degeneration - [Jennifer Heisz: Pioneering Brain Health Research and Inspiring Personal Journeys](https://www.bantingdiscoveryfoundation.ca/jennifer-heisz-pioneering-brain-health-research-and-inspiring-personal-journeys/) - Discover the groundbreaking work of Jennifer Heisz in brain health and aging. From her pivotal research in dementia prevention to her transformation from a sedentary scholar to an Ironman finisher, delve into her inspiring journey. - [Highlighting the "Status of Inclusion, Diversity, Equity and Accessibility (IDEA) in Canada’s Life Sciences Sector" Launch Event](https://www.bantingdiscoveryfoundation.ca/highlighting-the-status-of-inclusion-diversity-equity-and-accessibility-idea-in-canadas-life-sciences-sector-launch-event/) - Dive into key findings from the recent conference on Inclusion, Diversity, Equity, and Accessibility (IDEA) in Canada’s Life Sciences Sector. Discover recommendations and opportunities for a more inclusive future in the industry. - [Dr. Luka Milosevic: Championing Neuromodulation as New Co-Director of CRANIA](https://www.bantingdiscoveryfoundation.ca/dr-luka-milosevic-elevating-neuromodulation-research-and-advancing-dystonia-treatment/) - Celebrating the appointment of Dr. Luka Milosevic, a Banting award laureate, as the new Co-director of CRANIA. His profound expertise in biomedical engineering and human neurophysiology will be instrumental in advancing the field of neuromodulation research. - [Celebrating Canada Day: Innovating for a Healthier Future](https://www.bantingdiscoveryfoundation.ca/celebrating-canada-day-innovating-for-a-healthier-future/) - Celebrate Canada Day with Banting Research Foundation. Honoring Banting's legacy, we shape a healthier future through innovation. - [Honouring the Legacy of Indigenous Peoples](https://www.bantingdiscoveryfoundation.ca/honouring-the-legacy-of-indigenous-peoples/) - On National Indigenous Peoples Day, we honor the rich legacy of innovation and resilience of Indigenous communities. Join us as we highlight their pivotal role in shaping the world of research and our commitment to fostering stronger ties with Indigenous communities at the Banting Research Foundation. - [2023 Discovery Awardee: Erwan Pernet](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-erwan-pernet/) - Dr. Erwan Pernet, an Assistant Professor at the Université du Québec à Trois-Rivières (UQTR), has been recognized as a 2023 Banting Discovery Awardee for his pioneering work on bronchopulmonary dysplasia (BPD). - [2023 Discovery Awardee: Andrew Harris](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-andrew-harris/) - Dr. Andrew Harris, an assistant professor at Carleton University, is making significant strides in the field of biomechanics and platelet formation. He was recently recognized as a 2023 Banting Discovery Awardee, an honor given to outstanding early-career researchers in health and biomedical sciences in Canada. His research focuses on the mechanical properties of cells and tissues, with a special interest in how changes in the actin cytoskeleton impact cellular force generation and the formation of platelets. His work has the potential to lead to new approaches for generating platelets outside of the body and a better understanding of platelet disorders. - [2023 Discovery Awardee: Marie-Claude Sincennes](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-marie-claude-sincennes/) - Dr. Marie-Claude Sincennes, a renowned Professor at the Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), was recently honored with the prestigious Jarislowsky Fellowship-Banting Discovery Award for her exceptional contributions to the field of muscle stem cell biology. Her research, focusing on the role of genes influencing the onset and progression of neuromuscular diseases, offers new insights and opens new avenues for potential treatments. - [2023 Discovery Awardee: Eva Kaufmann](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-eva-kaufmann/) - Meet Dr. Eva Kaufmann, an Assistant Professor at Queen's University, recently honored as a 2023 Banting Discovery Awardee for her innovative research in immunology. Exploring the lasting impact of mold exposure on the immune system, Dr. Kaufmann's work holds tremendous potential for the future of immunology and infectious disease. Join us in celebrating her exceptional contributions to health and biomedical research. - [Spotlight on Leadership: Dr. Catharine Whiteside](https://www.bantingdiscoveryfoundation.ca/spotlight-on-leadership-catharine-whiteside/) - In this spotlight feature, we delve into the career of Dr. Catharine Whiteside, our Board Chair. From her pivotal role at Diabetes Action Canada to her influential research in kidney disorders, Dr. Whiteside's impact extends far beyond her leadership at the Banting Research Foundation. Read on to explore her journey of dedication, excellence, and inspiring leadership. - [2023 Discovery Awardee: Faith Brennan](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-faith-brennan/) - Discover the pioneering work of Dr. Faith Brennan, a Banting Discovery Awardee 2023. Her innovative research in neurological recovery could significantly enhance our understanding of the brain and spinal cord's immune responses following injuries. This in-depth profile explores her career, research, and the impact of her work on neurological disorders. - [2023 Discovery Awardee: Brice Batomen Kuimi](https://www.bantingdiscoveryfoundation.ca/2023-discovery-awardee-brice-batomen-kuimi/) - The Banting Research Foundation is proud to spotlight Dr. Brice Batomen Kuimi, an Assistant Professor of epidemiology at the Dalla Lana School of Public Health, University of Toronto, and recipient of the University of Toronto 100th Anniversary Discovery of Insulin Banting Award. His innovative research on traffic calming measures promises to significantly contribute to our understanding of public health and safety. - [Announcing the 2023 Banting Discovery Award Recipients](https://www.bantingdiscoveryfoundation.ca/announcing-the-2023-banting-discovery-award-recipients/) - Meet the 2023 Banting Discovery Awardees - exceptional Canadian researchers pioneering groundbreaking projects in the health and biomedical sciences. Learn more about their innovative work and join us in celebrating their achievements. Banting Research Foundation: Driving innovation in health research. - [A Resounding Success: The First Discovery Mentorship Open House](https://www.bantingdiscoveryfoundation.ca/discovery-mentorship-open-house-2023/) - Recap of the first-ever Discovery Mentorship Open House organized by the Banting Research Foundation, highlighting the event's success, engaging discussions, excellent venues, and delicious food. Learn more about the insightful IDEA presentation by Shift Health and the exciting future of research and mentorship. - [Unmasking Cardiometabolic Disease: Spotlight on Banting Discovery Awardee Dr. Kimberly Dunham-Snary](https://www.bantingdiscoveryfoundation.ca/unmaking-cardiometabolic-disease/) - Dr. Kimberly Dunham-Snary, Assistant Professor at Queen’s University and recipient of the prestigious Banting-Mitacs Discovery Award 2022, is exploring a novel concept in the field of cardiometabolic diseases—mitochondrial-metabolomic fingerprinting. This innovative approach could revolutionize how we understand, diagnose, and treat a range of heart and metabolic conditions. Her work exemplifies the pioneering spirit of Banting Research Foundation-supported research, pushing the boundaries of our knowledge to improve human health. By donating to the Banting Research Foundation, you are directly supporting promising Canadian early-career researchers and their innovative projects. Together, we can make a difference. Please consider making a donation today - [The Innovations of Dr. Jeffrey Leyton: Enhancing Cancer Treatment with Antibody-Conjugates](https://www.bantingdiscoveryfoundation.ca/developing-antibody-drug-conjugates-and-probes-for-treating-muscle-invasive-bladder-cancer/) - The Innovations of Dr. Jeffrey Leyton: Enhancing Cancer Treatment with Antibody-Conjugates Dr. Leyton’s multidisciplinary research involves chemistry, biology, and physics. His laboratory works on antibodies (functionalization – engineering), antibody conjugation chemistry (cargo attachment), endosome escape mechanism for antibodies, intracellular trafficking control, life science and health applications, and more. In conclusion, Dr. Leyton’s research on antibody-conjugates and - [Improving immune cells: INRS researchers make breakthrough in HIV-1 treatment](https://www.bantingdiscoveryfoundation.ca/improving-immune-cells-inrs-researchers-make-breakthrough-in-hiv-1-treatment/) - Banting Discovery Awardee Discovers New Therapeutic Approach for HIV-1 Treatment: INRS Team Identifies a Key Metabolic Advantage for Immune Cells Researchers from the Institut national de la recherche scientifique (INRS) have made a significant breakthrough in finding a therapeutic approach to restore the effectiveness of immune cells in people infected with HIV-1. The study, published - [The Banting Research Foundation Celebrates 100 Years Since Banting's Nobel Prize Win​](https://www.bantingdiscoveryfoundation.ca/the-banting-research-foundation-celebrates-100-years-since-bantings-nobel-prize-win/) - The Banting Research Foundation Celebrates 100 Years Since Banting's Nobel Prize Win This year marks the 100th anniversary of Sir Frederick Banting’s Nobel Prize win for the discovery of insulin. The Banting Research Foundation, established to honor his legacy, is commemorating this important milestone. Banting’s discovery of insulin revolutionized the treatment of diabetes, which at - [Canada must urgently invest in research into the health impacts of climate change [Toronto Star]](https://www.bantingdiscoveryfoundation.ca/canada-must-urgently-invest-in-research-into-the-health-impacts-of-climate-change-toronto-star/) - To continue reading about the need to increase funding for early-career researchers, click here for the article on the Toronto Star's website. - [Celebrating International Women's Day](https://www.bantingdiscoveryfoundation.ca/celebrating-international-womens-day/) - We were honored to have been invited to the Elegant International Women's Day Charity Concert with the Toronto Elegant Lions Club, in support of the Banting Research Foundation. - [From the Lab to the Gym: Translating Scientific Discoveries About Exercise and Cognition into Real-World Applications](https://www.bantingdiscoveryfoundation.ca/the-benefits-of-exercise-for-brain-health/) - From the Lab to the Gym: Translating Scientific Discoveries About Exercise and Cognition into Real-World Applications Matthieu Boisgontier, an associate professor at the University of Ottawa, and past Banting Discovery Award recipient, led a new study looking at the link between exercise and memory. His study analyzed data for almost 350,000 people to show that - [The Banting Foundation successfully auctioned two landscape paintings by Sir Frederick Banting](https://www.bantingdiscoveryfoundation.ca/auction-paintings/) - Congratulations on a successful auction! The Banting Foundation is very grateful for the kind support of the Heffel Fine Art auction in the selling of two landscape paintings by Sir Frederick Banting. The auction on November 24, 2022 raised funds in support of our Discovery Award program for early career biomedical investigators.Heffel Fine Art Auction graciously - [LAURÉATES ET LAURÉATS DES PRIX DÉCOUVERTE BANTING 2022](https://www.bantingdiscoveryfoundation.ca/laureates-et-laureats-des-prix-decouverte-banting-2022/) - English La Fondation de recherche Banting a récemment annoncé les six remarquables récipiendaires des Prix Découverte 2022. Offrant une subvention d’un an pouvant aller jusqu’à 30 000 $, ces prix récompensent les idées audacieuses de la fine fleur de la recherche en sciences de la santé et biomédicales innovantes dans le cadre d’un concours fondé sur l’évaluation par - [2022 Discovery Award Recipients Announced](https://www.bantingdiscoveryfoundation.ca/2022-winners-announced/) - Français Toronto, ON – The Banting Research Foundation recently announced the outstanding six recipients of the 2022 Discovery Awards. This award, a one-year grant of up to $30,000, recognizes the highest ranked applicants in an annual peer-reviewed competition for their big bold ideas in innovative health and biomedical research. The award presented since 1925 marks for - [In the global race for science talent, is Canada investing enough? [Policy Options]](https://www.bantingdiscoveryfoundation.ca/in-the-global-race-for-science-talent-is-canada-investing-enough/) - To read more about the global race for science talent, click here for the opinion-editorial on Policy Option's website. - [Other countries are investing in young researchers. Canada must up its game or fall behind [Toronto Star]](https://www.bantingdiscoveryfoundation.ca/other-countries-are-investing-in-young-researchers-canada-must-up-its-game-or-fall-behind-toronto-star/) - To read more about this piece, click here for the article on the Toronto Star. - [Canada can’t afford to leave research out of the innovation conversation [The Hill Times]](https://www.bantingdiscoveryfoundation.ca/canada-cant-afford-to-leave-research-out-of-the-innovation-conversation-the-hill-time/) - To continue reading about the need to further fund innovation, click here for the article on The Hill Times' website. - [New Mitacs-Banting Fellowship Program will Address Climate Change, Health and Equity](https://www.bantingdiscoveryfoundation.ca/new-mitacs-banting-fellowship-program-will-address-health-inequities-due-to-climate-change/) - Toronto — A new partnership between Mitacs and the Banting Research Foundation will address health disparity and inequality in Canada to support postdoctoral scholars in research to reduce the health risks and inequities caused by climate change. The Mitacs-Banting Discovery Postdoctoral Fellowship will help Canada lead the world in understanding the links between health, equity, - [Banting-CANSSI Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/banting-canssi-discovery-award-winner/) - The Banting Research Foundation and CANSSI Ontario are pleased to announce that the 2021 Discovery Award in Data Science scholars are Drs. Glen McGee and Alanna Weisman. Dr. Glen McGee intends to develop statistical tools to characterize and correct biases that arise from the analysis of electronic health records of patients with autism spectrum disorder. - [Announcing the 2021 Discovery Awards](https://www.bantingdiscoveryfoundation.ca/96th-annual-banting-discovery-award-winners-are-here/) - Toronto, ON – Mitacs and the Banting Research Foundation are proud to announce the winners of the 96th Annual Banting Research Foundation Discovery Awards. This year, 12 investigators – 50% of whom are women – have been awarded one-year grants of up to $25,000 for innovative health and biomedical research projects. The goal of this - [96th Annual Banting Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/2021-discovery-awards-winners-are/) - Every year, the Foundation presents six awards but this year is special. To mark the centenary year of the discovery of insulin, we have partnered with Mitacs to double the number of awards. A very special thanks to our partners Mitacs, Jarislowsky Foundation and the Centre of Canadian Statistical Sciences Institute (CANSSI) Ontario, and all - [Remembering Banting Alumni, "founding father of genetics"...](https://www.bantingdiscoveryfoundation.ca/remembering-banting-alumni-founding-father-of-genetics/) - Dr. Lou Siminovitch (Discovery Award recipient 1958) was a lover of science – an outstanding Canadian scientist who made brilliant contributions to cell virology, stem cell research and the field of genetics. As a scientific visionary, he mentored and influenced several generations of scientists, which will surely have a lasting impact for generations to come. Dr. Siminovitch also held positions - [New Mitacs-Banting Discovery Awards invest in early career researchers](https://www.bantingdiscoveryfoundation.ca/new-mitacs-banting-discovery-awards-invest-in-early-career-researchers/) - OTTAWA -- Mitacs is expanding its support for early career researchers across Canada by funding six new Banting Research Foundation Discovery Awards, valued at $25,000 each, for researchers in the first three years of a faculty position following their post-doctoral fellowship. The new Mitacs-Banting Discovery Awards are for researchers in biomedical sciences undertaking health research - [Reduce or Prevent Rheumatoid Arthritis...see what Dr. Ali Abdul-Sater has to say...](https://www.bantingdiscoveryfoundation.ca/reduce-or-prevent-rheumatoid-arthritis-see-what-dr-ali-sater-has-to-say/) - York University Team Works to Reduce or Prevent Rheumatoid Arthritis TRAF1 is a protein our bodies make naturally, and people with a specific variation of TRAF1 have an increased risk of developing rheumatoid arthritis. Removing or adjusting TRAF1 to reduce risk is complex—because this protein has other important roles in our immune system. Our bodies - [Combat a deadly fungal pathogen with gene-editing technology (CRISPR-Cas)...](https://www.bantingdiscoveryfoundation.ca/combat-a-deadly-fungal-pathogen-with-dna-editing-crispr-technology/) - While the public is aware of the potentially deadly pathogens invading our hospitals, such as the highly infectious agents C. difficile or drug resistant Staph aureus (MRSA), a newer and much lesser known fungal pathogen has been emerging. This deadly, multidrug resistant organism, Candida Auris is now causing outbreaks in healthcare settings, like hospitals or - [Announcing the 2020 Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/2020-discovery-award-recipients/) - The 95th Annual Banting Research Foundation Discovery Awards honour seven investigators for new projects in innovative health and biomedical research. Each award is valued up to $25,000. The Foundation is pleased to note the 62 applications received were divided equally between male and female-identified researchers As well, a total of 14 applications were ranked either - [Banting-CANSSI Discovery Award Winner!](https://www.bantingdiscoveryfoundation.ca/banting-canssi-award-in-data-science-2020-winner/) - The Banting Foundation and CANSSI Ontario are pleased to announce the first Discovery Award in Data Science Scholar: Dylan Kobsar, who is Assistant Professor of Neuromechanics in the Department of Kinesiology at McMaster University. Dr. Kobsar received this year's award for his project titled: Stepping out of the lab: New methods to translate movement analyses into - [2019 Discovery Award Recipients](https://www.bantingdiscoveryfoundation.ca/2019-discovery-award-recipients/) - We are thrilled to announce the Banting Research Foundation 2019 Discovery Award recipients! This year, we were able to fund six projects from outstanding applicants, chosen out of 79 applications. These applicants were the highest ranking in our 2019 peer-reviewed competition. The Banting Research Foundation Discovery Award is unique in that it it focuses on early-career - [2020 Banting Research Foundation/ McLaughlin Centre Discovery Award](https://www.bantingdiscoveryfoundation.ca/2020-banting-research-foundation-mclaughlin-centre-discovery-award/) - The Banting Research Foundation and the University of Toronto McLaughlin Centre are pleased to announce that the application period is now open for the 2020 Banting Research Foundation/ McLaughlin Centre Discovery Award. This marks the fourth year of a funding partnership to support research by early career investigators focused on areas relevant to genomic medicine. - [Discovery Awardee Profile - Dr. Gareth Lim](https://www.bantingdiscoveryfoundation.ca/gareth-lim/) - By Krista Lamb - While we often think of obesity as a condition related to diet and exercise, the reality is that it’s much more complicated than just those two things. Many people who develop obesity will do so because of a myriad of complex factors, including metabolic or genetic issues. They may, in turn, - [Lindsay Bodell brings her science to the public](https://www.bantingdiscoveryfoundation.ca/lindsay-bodell-brings-her-science-to-the-public/) - The Royal Canadian Institute for Science (RCIScience) recently held a public event in Toronto exploring the science behind dieting and healthy eating. The event entitled, “New Year New You: The Science of Healthy Eating,” featured a panel discussion with four scientists with diverse expertise in nutrition, psychology, and science communication. Included in this panel was - [Updates from the 2018 Discovery Awardees](https://www.bantingdiscoveryfoundation.ca/2018-updates/) - With generous support from donors and volunteers in 2018, we supported 9 outstanding early career researchers across Canada. These researchers have since made significant progress on their research projects, expanded their research teams, received additional honours and awards, and secured longer-term funding from other granting agencies! Here are some updates from the 2018 Discovery Awardees: - [Launching Discovery - September 10, 2019](https://www.bantingdiscoveryfoundation.ca/launching-discovery-september-10-2019/) - On Tuesday September 10th, award recipients, volunteers, and friends of The Banting Research Foundation came together to celebrate a fantastic year at the Foundation. Dr. Susan George (1988 Award recipient) shared with us how critical funding from The Banting Research Foundation at an early stage of her career allowed her to yield promising data, which - [Recipient of the 2019 Discovery Award supported by Dystonia Medical Research Foundation Canada](https://www.bantingdiscoveryfoundation.ca/2019-discovery-award-supported-by-dmrf/) - The 2019 Banting Research Foundation Discovery Award supported by Dystonia Medical Research Foundation (DMRF) Canada has been awarded to Dr. Nicholas Strzalkowski from the Department of Biology at Mount Royal University. The Banting Research Foundation and DMRF Canada are thrilled to be able to partner to support this outstanding early career investigator whose research focuses - [Nicholas Strzalkowski, PhD](https://www.bantingdiscoveryfoundation.ca/nicholas-strzalkowski-phd/) - Department of Biology, Mount Royal University – Sensory Feedback in Dystonia Muscle sensory feedback is thought to contribute to dystonia, however this has not been investigated directly. Dr. Strzalkowski’s research group believes that abnormal sensory feedback from specialized muscle receptors contributes to the involuntary dystonic muscle contractions and is associated with botulinum toxin treatment outcomes. Dr. - [Salim Islam, PhD](https://www.bantingdiscoveryfoundation.ca/salim-islam-phd/) - Department of Microbiology and Biotechnology, INRS – Institut Armand-Frappier Bacterial social networking via outer-membrane extrusion: towards an understanding of colonization and persistence Bacteria can colonize both living and non-living surfaces, leading to the development of a microbial community. However, the manner in which different types of bacterial cells interact with each other in such densely-populated - [Lindsay Bodell, PhD](https://www.bantingdiscoveryfoundation.ca/lindsay-bodell-phd/) - Department of PsychologyWestern University Negative Affect and Reward Processing in Individuals with Binge Eating Binge eating is defined by consuming a large amount of food over a short time period and feeling out of control while eating. This behavior is a key feature of eating disorders, affects approximately 10% of the population, and is associated - [Craig Bailey, PhD](https://www.bantingdiscoveryfoundation.ca/craig-bailey/) - Department of Biomedical Sciences, University of Guelph Nicotinic receptor signaling in a mouse model of Fetal Alcohol Spectrum Disorder Chronic prenatal exposure to alcohol can produce a spectrum of adverse effects known collectively as Fetal Alcohol Spectrum Disorder (FASD). Although deficits in attention rank among the most common and persistent components of FASD, mechanisms underlying - [Banting's Legacy - Art & Science of Discovery](https://www.bantingdiscoveryfoundation.ca/bantings-legacy-art-science-of-discovery/) - In September 2016, the Banting Research Foundation welcomed 60 guests to a celebration of Banting's Legacy, the Art and Science of Discovery. Frederick Banting's accomplishments as a scientist and an artist inspired the theme for the evening. The reception honoured Janet Rossant, CC, PhD, FRS, FRSC, recipient of the 2016 Henry G Friesen International Prize in - [Jonathan Perreault, PhD](https://www.bantingdiscoveryfoundation.ca/jonathan-perreault/) - INRS - Institut Armand Frappier Regulation in the opportunistic pathogen Burkholderia by the MAEB RNA motif Aside from their role in storing hereditary information, DNA and RNA are now known to have many more functions. Living organisms have a plethora of RNAs that control numerous processes in cells. One such RNA, named MAEB, was recently - [Takako Niikura, DVM PhD](https://www.bantingdiscoveryfoundation.ca/takako-niikura/) - Faculty of Health Sciences, Simon Fraser University Regulation of amyloid beta metabolism In Alzheimer's disease (AD), progressive brain atrophy and dementia appear because of neuronal cell death and synaptic dysfunction in brains. Amyloid beta plays a central toxic role in AD pathogenesis. Combination of the direct suppression of neuronal death and removal of amyloid beta - [Tara Moriarty, PhD](https://www.bantingdiscoveryfoundation.ca/tara-moriarty/) - Matrix Dynamics Group, Faculty of Dentistry, University of Toronto Vascular adhesion mechanisms of the Lyme disease spirochete Blood-borne spread (dissemination) of pathogens is a critical step in the development of serious infectious disease, and is responsible for most of the mortality due to bacterial infection. The dissemination mechanisms of many bacterial pathogens are largely unknown. A - [Simon Lees, PhD](https://www.bantingdiscoveryfoundation.ca/simon-lees/) - Faculty of Medicine, Lakehead University The IL-6 paradox in the development of insulin resistance Paradoxically, elevated IL-6 is associated with insulin resistance and type 2 diabetes, while at the same time strong evidence supports the notion that IL-6 may facilitate improved insulin signaling as a result of physical activity. The proposed research will determine the - [Marcelo Berlim, MD](https://www.bantingdiscoveryfoundation.ca/marcelo-berlim/) - Department of Psychiatry, McGill University Remediating decision-making deficits in depressed subjects at high risk for suicide with transcranial magnetic stimulation We aim to assess whether high frequency repetitive transcranial magnetic stimulation, a safe and non-invasive method for modulating the activity of specific brain regions, when applied over the left region of the forehead (ie, the - [Michelle Scott, PhD](https://www.bantingdiscoveryfoundation.ca/michelle-scott/) - Department of Biochemistry, Université de Sherbrooke Characterization of a novel function of small RNAs in alternative splicing The process of alternative splicing allows the production of multiple distinct proteins from a single gene, in a manner that can be cell-type specific. Alternative splicing requires an extensive and complex regulation. Diverse human diseases can be caused - [Martin Lévesque, PhD](https://www.bantingdiscoveryfoundation.ca/martin-levesque/) - Department of Psychiatry and Neurosciences, Université Laval Molecular mechanisms of axon guidance mediated by PlexinC1 in dopamine neuron axonal projections Degeneration of midbrain dopaminergic neurons (mDA) is the principal cause of Parkinson's disease. Grafts of dopaminergic neurons newly generated from stem cells represent a promising therapeutic avenue. However, inappropriate re-innervation of the grafted neurons represents - [Carl Ernst, PhD](https://www.bantingdiscoveryfoundation.ca/carl-ernst/) - Department of Psychiatry, McGill University Functional analysis of the 16p11.2 locus using patient-derived induced-pluripotent stem cells Large deletions of DNA on chromosome 16 are associated with Autism Spectrum Disorders (ASD) in about 1% of all Canadians with autism, and many more Canadians with intellectual disability. I have recruited and clinically assessed two independent families carrying - [Alexandre Douplik, PhD](https://www.bantingdiscoveryfoundation.ca/alexandre-douplik/) - Physics Department, Ryerson University Surface-enhanced Raman fiber sensor for endoscopic early detection of tumor-related biomolecules in gastroenterology The goal of the project is development of surface-enhanced Raman spectroscopy fiber probes for high sensitive and rapid non-invasive diagnostics including malignancy detection. Optical sampling of biological molecules can detect specific Raman "fingerprints" including cancer "signatures" with high - [Margaret K Hahn, MD PhD](https://www.bantingdiscoveryfoundation.ca/margaret-k-hahn/) - Centre for Addiction and Mental Health Central insulin to prevent olanzapine-induced adiposity: a rodent model Atypical antipsychotic (AAP) medications, the mainstay treatment for psychosis and schizophrenia, are defined by weight gain and metabolic problems that likely contribute to a 2-fold increase in cardiovascular (CV) deaths in this population. Lifestyle interventions often have limited success, and - [Dennis Jensen, PhD](https://www.bantingdiscoveryfoundation.ca/dennis-jensen/) - Department of Kinesiology & Physical Education, McGill University Physiological mechanisms of dyspnea relief and improved exercise tolerance after treatment with oral morphine in patients with advanced chronic obstructive pulmonary disease (COPD) Chronic obstructive pulmonary disease (COPD) is a progressive disease of the lungs and airways, causing shortness of breath (dyspnea) and exercise intolerance. Conventional efforts - [David Chatenet, PhD](https://www.bantingdiscoveryfoundation.ca/david-chatenet/) - Centre INRS–Institut Armand-Frappier Design and synthesis of peptide inhibitors of PqsE as novel antibacterial therapeutics Pseudomonas aeruginosa (Pa), a prevalent opportunistic human pathogen responsible for morbidity and mortality among individuals suffering from cystic fibrosis, is notorious for its high resistance to antibiotic treatments. As recently demonstrated, cell-to-cell signaling regulated by the PqsE enzyme plays a - [Marie-Ève Tremblay, PhD](https://www.bantingdiscoveryfoundation.ca/marie-eve-tremblay/) - Département de médecine moléculaire, Université Laval Microglial relationships with synaptic elements in Alzheimer's disease A series of recent discoveries have challenged our view of microglia, the brain immune cells, showing unexpected roles in the active maintenance of neuronal circuits throughout the lifespan. Contributing to this nascent field of investigation, this project aims at exploring the - [Dave Richard, PhD](https://www.bantingdiscoveryfoundation.ca/dave-richard/) - Département de microbiologie-infectiologie et d'immunologie, Université Laval Protein trafficking to the apical complex of the malaria parasite Malaria is one of the world's most common infectious diseases, with approximately 274 million cases each year and 1 million deaths, and thus represents one of the most devastating global public health problems. The lack of an effective - [Pierre-Yves Lozach, PhD](https://www.bantingdiscoveryfoundation.ca/pierre-yves-lozach/) - Centre INRS – Institut Armand-Frappier Bunyavirus entry into mammalian cells Bunyaviridae is a large family of viruses mainly transmitted by arthropods such as mosquitos and ticks. Many bunyaviruses are important pathogens in humans and livestock. Due to their mode of transmission, they are considered emerging agents of diseases. Unfortunately, bunyaviruses are understudied, which has contributed to - [Emanuel Rosonina, PhD](https://www.bantingdiscoveryfoundation.ca/emanuel-rosonina/) - Department of Biology, York University Regulation of transcription and splicing factors by sumoylation SUMO is a protein modification that plays important roles in regulating many cellular processes. Several proteins that are involved in neurodegenerative disease are modified by SUMO, and abnormal protein modifications by SUMO have been implicated in many types of cancer, indicating that - [Ewa Niechwiej-Szwedo, PhD](https://www.bantingdiscoveryfoundation.ca/ewa-niechwiej-szwedo/) - Department of Kinesiology, University of Waterloo The role of binocular vision in the development of fine motor skills Seeing in depth is essential for guiding purposeful movements, such as reaching and grasping for toys or food, catching a ball or using tools to accomplish complex tasks. Binocular vision provides important cues for 3D depth perception. - [Jeffrey Leyton, PhD](https://www.bantingdiscoveryfoundation.ca/jeffrey-leyton/) - Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke An advanced development in targeted radiation against muscle invasive migrating bladder cancer cells Bladder cancer affects thousands of Canadians on an annual basis. Unfortunately, bladder cancer remains one of the most difficult cancers to manage. The treatment options currently available to patients with muscle invasive bladder - [Jennifer Heisz, PhD](https://www.bantingdiscoveryfoundation.ca/jennifer-heisz/) - Department of Kinesiology, McMaster University Examining the dose-response relationship between physical exercise and cognitive function in older adults Alzheimer's disease is the most common form of dementia, causing severe cognitive impairment and interfering with daily life. As the population ages, the number of Canadians living with dementia is projected to double within a generation to - [Yannick Doyon, PhD](https://www.bantingdiscoveryfoundation.ca/yannick-doyon/) - Department of Molecular Medicine, Université Laval In vivo genome editing as a novel class of human therapeutics to treat pediatric metabolic disorders Genetic disorders in children are individually rare but collectively frequent, affecting the lives of approximately 500,000 children in Canada. They often are serious, life threatening or fatal, but because each rare disease affects - [Benoît Arsenault, PhD](https://www.bantingdiscoveryfoundation.ca/benoit-arsenault/) - Department of Medicine, Université Laval Impact of a lifestyle modification program on high-density lipoprotein function Plasma levels of high-density lipoprotein (HDL) cholesterol, often referred to as “the good cholesterol”, are inversely associated with cardiovascular disease and type 2 diabetes risk. Several lines of evidence suggest that these associations could be explained by the fact that - [Michael Suits, PhD](https://www.bantingdiscoveryfoundation.ca/michael-suits/) - Department of Chemistry and Biochemistry, Wilfrid Laurier University Protein structure-function relationships in periodontal disease In the mouth, a wide variety of microorganisms are embedded in biofilms that contribute to periodontal diseases such as gum disease and tooth decay. To understand the contribution of a consortium of periodontal pathogens, including Porphyromonas gingivalis, Tannerella forsythia, and Treponema - [Catherine Martel, PhD](https://www.bantingdiscoveryfoundation.ca/catherine-martel/) - Department of Medicine, Université de Montréal/ Montreal Heart Institute Research Centre Lymphatic vessel function in atherosclerosis High blood cholesterol is an important risk factor for cardiovascular diseases such as atherosclerosis. High-density lipoprotein (HDL) is called "good cholesterol" because it transports cholesterol away from tissues, such as the blood vessel walls, carrying cholesterol through the blood - [Joon Lee, PhD](https://www.bantingdiscoveryfoundation.ca/joon-lee/) - School of Public Health and Health Systems, University of Waterloo Personalized predictive analytics based on electronic medical data and patient similarity metrics As hospitals and doctors’ offices in Canada rapidly adopt electronic medical records (EMRs), the enormous clinical value of ever-increasing EMR data is receiving the spotlight. In particular, massive EMR data can facilitate personalized - [Morgan Langille, PhD](https://www.bantingdiscoveryfoundation.ca/morgan-langille/) - Department of Pharmacology, Dalhousie University Design and implementation of a human microbiome interaction database It is becoming increasingly apparent that the microbes living on and in our bodies, called the human microbiome, are important for human health. These microbes help with the digestion of food, defend against unwanted pathogens, stimulate and keep our immune systems - [Petra Kienesberger, PhD](https://www.bantingdiscoveryfoundation.ca/petra-kienesberger/) - Department of Biochemistry and Molecular Biology, Dalhousie University Role of the adipokine autotaxin in obesity-associated insulin resistance Insulin resistance, a major complication of obesity, is a condition where tissues such as skeletal muscle become unresponsive to the blood sugar-lowering hormone insulin. Insulin resistance can lead to type 2 diabetes, which is associated with a shorter - [Jeremy Hirota, PhD](https://www.bantingdiscoveryfoundation.ca/jeremy-hirota/) - Department of Medicine, University of British Columbia A 3D-printed human airway model for studying respiratory mucosal immune responses Exposure to allergens and air pollutants in the air we breathe can lead to “lung attacks” in individuals with lung diseases, but it is unclear how this happens and what we can do to stop it. Dr - [Jeffrey Chen, PhD](https://www.bantingdiscoveryfoundation.ca/jeffrey-chen/) - VIDO-InterVac, University of Saskatchewan Towards a next generation of superior BCG tuberculosis vaccines Tuberculosis is a serious global health problem, with one-third of the world’s population having been infected by the infectious agent, Mycobacterium tuberculosis. The only available tuberculosis vaccine, live M. bovis BCG vaccine, has an excellent record in protecting infants, but works poorly - [Roxane Paulin, PhD](https://www.bantingdiscoveryfoundation.ca/roxane-paulin/) - Department of Medicine, Université Laval Targeting ErbB2 by TAK-165 reverses pulmonary hypertension in vitro and in vivo In pulmonary hypertension (high blood pressure in the lungs), cells forming the walls of arteries in the lungs proliferate like cancer cells, narrowing the arteries and making it difficult for blood to pass through. There is also evidence - [Noam Miller, PhD](https://www.bantingdiscoveryfoundation.ca/noam-miller/) - Department of Psychology, Wilfrid Laurier University Exploring neural mechanisms of social behavior using zebrafish (Danio rerio) This research study uses zebrafish, a small freshwater species of fish commonly used in genetic and developmental research, to explore the mechanisms of social behavior. Zebrafish spend the majority of their time in groups and have complex social interactions, - [Janet Rossant, CC PhD FRS FRSC](https://www.bantingdiscoveryfoundation.ca/janet-rossant/) - Janet Rossant is a world-renowned expert in developmental biology. Funded by the Banting Research Foundation in 1983, while at Brock University, for her early research in developmental biology, she has become a global leader in understanding the role of genes in embryo development. Her work has been fundamental in the development of human pluripotent stem - [Adolfo J. de Bold, OC PhD FRSC](https://www.bantingdiscoveryfoundation.ca/adolfo-de-bold/) - Adolfo de Bold is a cardiovascular researcher, best known for his discovery of atrial natriuretic factor (ANF), a polypeptide hormone secreted by heart muscle cells. He was funded by the Banting Research Foundation in 1980 for his studies on storage granules in atrial heart cells. The resulting discovery and isolation of atrial natriuretic factor changed - [Kaitlyn McLachlan, PhD](https://www.bantingdiscoveryfoundation.ca/kaitlyn-mclachlan/) - Department of Psychology, University of Guelph Evaluating novel neurobiomarkers in the identification of adults with FASD using portable eye tracking and EEG technology Individuals with fetal alcohol spectrum disorder (FASD) are overrepresented in the criminal justice system. There is an urgent need to identify neurobiomarkers of FASD and individuals at risk in order to reduce - [Jeffrey Gagnon, PhD](https://www.bantingdiscoveryfoundation.ca/jeffrey-gagnon/) - Department of Biology, Laurentian University Investigating the role of H2S in the regulation of ghrelin secretion Ghrelin, a hormone produced in the endocrine cells of the stomach, regulates several aspects of metabolic health, including appetite and energy storage. Recently, meals high in the amino acid cysteine have been shown to reduce ghrelin secretion. Foods rich - [Christopher Dennison, PhD](https://www.bantingdiscoveryfoundation.ca/christopher-dennison/) - Department of Mechanical Engineering, University of Alberta Impact severity metric for focal head and diffuse brain injury Whether or not today’s helmets protect the wearer from mild diffuse brain injuries, sometimes referred to as concussions, is the topic of intense debate. One of the primary venues for this debate is in the helmet standards and - [Jeanette Boudreau, PhD](https://www.bantingdiscoveryfoundation.ca/jeanette-boudreau/) - Department of Microbiology and Immunology, Dalhousie University Directing natural killer cell cytotoxicity to the tumour's susceptibilities Natural killer (NK) cells are white blood cells that kill tumours. The potential of each NK cell to kill tumours is counterbalanced by its ability to be inhibited by healthy cells through its inhibitory receptors. Dr Boudreau aims to - [Funding the first clinical trials of heparin](https://www.bantingdiscoveryfoundation.ca/first-clinical-trials-of-heparin/) - The Banting Research Foundation funded the first clinical trials of heparin in 1935. Heparin is a powerful anticoagulant that is widely used in open-heart and organ transplant surgery to prevent the formation of blood clots. It was purified in the early 1930s in Toronto under the direction of Dr Charles H Best. It was then - [Florian Bentzinger, PhD](https://www.bantingdiscoveryfoundation.ca/florian-bentzinger-phd/) - Department of Pharmacology-Physiology, Université de Sherbrooke Niche regulation of muscle stem cell specification Dr Bentzinger’s group studies the role of regulatory signals in the microenvironment where skeletal muscle stem cells (MuSCs) reside. Understanding how this so-called "stem cell niche" controls MuSCs and how these instructive mechanisms become disrupted in aging and disease, could help in - [Jennifer Gordon, PhD](https://www.bantingdiscoveryfoundation.ca/jennifer-gordon-phd/) - Department of Psychology, University of Regina HPA axis dysregulation in the etiology of perimenopausal depression Women are 2-4 times more likely to develop depression during perimenopause, the menopause transition phase, than at any other time in their lives. Dr Gordon proposes that increased estrogen fluctuation during this phase may trigger dysregulation of the hypothalamic-pituitary-adrenal (HPA) - [Catherine Larochelle, MD PhD](https://www.bantingdiscoveryfoundation.ca/catherine-larochelle-md-phd/) - CRCHUM, Department of Neurosciences, Université de Montréal Molecular mechanisms underlying T lymphocytes interactions with oligodendrocytes in neuroinflammation In multiple sclerosis (MS), there is an abnormal response of immune cells against cells of the brain and spinal cord. Oligodendrocytes, the myelin-producing cells that support and insulate neurons, are injured by the inflammatory response, leaving neurons vulnerable. - [Gareth Lim, PhD](https://www.bantingdiscoveryfoundation.ca/gareth-lim-phd/) - CRCHUM, Department of Medicine, Université de Montréal Evaluating the therapeutic potential of 14-3-3ζ for the treatment of obesity Approximately 25% of Canadians are either overweight or obese. Current therapies have only modest success in reducing body weight, and surprisingly, none directly target fat cells, which are key in the development of obesity. Fat cells require - [Adena Scheer, MD](https://www.bantingdiscoveryfoundation.ca/adena-scheer-md/) - Department of Surgery, St Michael’s Hospital, Li Ka Shing Knowledge Institute, and the University of Toronto Cross-cultural communications in breast cancer treatment Among minorities, disparities in breast cancer treatments have been demonstrated across the developed world and have been associated with worse cancer outcomes. In Canada we have the highest rate of foreign-born individuals among - [Julien van Grevenynghe, PhD](https://www.bantingdiscoveryfoundation.ca/julien-van-grevenynghe-phd/) - Department of Infectious diseases, immunity, cancer and epidemiology, INRS – Institut Armand-Frappier and the Université du Québec Autophagy regulates CD8 T-cell killing activity during chronic HIV-1 infection Autophagy, a natural self-destructive process in cells, eliminates some viruses from cells, and also plays a role in shaping functions of T cells, a primary part of the - [Ali Abdul-Sater, PhD](https://www.bantingdiscoveryfoundation.ca/ali-abdul-sater-phd/) - School of Kinesiology and Health Science, York University Dissecting the role of TRAF1 in regulating inflammatory and autoimmune diseases Autoimmune diseases like Rheumatoid Arthritis (RA) are largely driven by abnormal inflammatory responses. Recent research from Dr Abdul-Sater’s group showed that TRAF1, an immune signaling molecule associated with increased risk to RA, can control inflammation. They - [Kyle Biggar, PhD](https://www.bantingdiscoveryfoundation.ca/kyle-biggar-phd/) - Department of Biology, Carleton University Identification of new substrates of the histone methyltransferase enzyme, SMYD3, and their implication in lung cancer development Lysine methylation plays a critical role in the development of many human diseases. These small chemical protein modifications allow cells to exert greater control over protein function. Importantly, proteins that control this lysine - [Dylan Cooke, PhD](https://www.bantingdiscoveryfoundation.ca/dylan-cooke-phd/) - Department of Biomedical Physiology and Kinesiology, Simon Fraser University Accelerated mapping of individual variation in brain organization with online detection of EMG activity Individuality is widely celebrated in human culture but rarely studied in the laboratory. As with dexterity and athletic coordination, brain organization varies significantly between individuals, though it is not known whether “natural - [Nomazulu Dlamini, MD PhD](https://www.bantingdiscoveryfoundation.ca/nomazulu-dlamini-md-phd/) - Division of Neurology, The Hospital for Sick Children Neural network reorganization and maladaptive plasticity in dystonia post childhood basal ganglia stroke Dystonia is a disabling and often painful disorder characterized by involuntary, repetitive muscle contractions, twisting movements and abnormal posturing. It is often resistant to treatment, and many children with dystonia develop fixed deformities with - [Robert Huber, PhD](https://www.bantingdiscoveryfoundation.ca/robert-huber-phd/) - Department of Biology, Trent University Using the social amoeba Dictyostelium discoideum to study neuronal ceroid lipofuscinosis Mutations in CLN5 cause late-infantile, juvenile, and adults forms of neuronal ceroid lipofuscinosis (NCL), commonly known as Batten disease. This devastating neurological disorder, which is linked to mutations in 13 genetically distinct genes, affects all ages and ethnicities and - [Ian Rodrigue-Gervais, PhD](https://www.bantingdiscoveryfoundation.ca/ian-rodrigue-gervais-phd/) - Department of Infectious Diseases, INRS - Institut Armand-Frappier Function of mitochondrial proteases on inflammation and necrosis in influenza virus pathogenesis Every year, people fall ill with the flu, a respiratory disease caused by the influenza virus. Our main tools for fighting deadly flu outbreaks are vaccines and antiviral drugs. But, despite their availability in Canada, - [Rebecca Shapiro, PhD](https://www.bantingdiscoveryfoundation.ca/rebecca-shapiro-phd/) - Department of Molecular and Cellular Biology, University of Guelph Genetic and functional genomic analysis of antifungal drug resistance in Candida auris Combating infectious disease pathogens is a pressing global health challenge. Due to limited treatment options, fungal pathogens pose a unique challenge, and are emerging as a leading cause of human mortality. The proposed research - [John Trant, PhD](https://www.bantingdiscoveryfoundation.ca/john-trant-phd/) - Department of Chemistry and Biochemistry, University of Windsor Dendronized enzymatically-resistant carbohydrate vaccines for treating lung cancer Therapeutic vaccines incorporating sugar molecules could provide new cancer treatments. Because over 85% of carcinoma cancer cells, regardless of organ, display the same few sugars on their surface, sugars not found on healthy cells, these sugars are promising targets - [Andrea Bombak, PhD](https://www.bantingdiscoveryfoundation.ca/andrea-bombak-phd/) - Department of Sociology, University of New Brunswick Intersections of Weight Stigma in New Brunswick Weight stigma affects risk for stress, diabetes, and heart disease. Little research has explored how people facing other stigmas (like racism, ageism, or classism) are affected by weight stigma. Place also affects health by making it easier or more difficult to access - [Mahsa Jessri, PhD](https://www.bantingdiscoveryfoundation.ca/mahsa-jessri-phd/) - Department of Food, Nutrition, and Health, University of British Columbia Dietary Patterns and Food Policies: Measuring the Impact on Health With the dramatic increase in life expectancy that occurred during the 20th century, we can be more optimistic than ever that good health is both achievable and sustainable. Unlike smoking, whose contribution to death and - [Benoit Laurent, PhD](https://www.bantingdiscoveryfoundation.ca/benoit-laurent-phd/) - Department of BiochemistryUniversité de Sherbrooke Deciphering the epigenetic regulation of alternative splicing in neurons Aging can reduce the birth of new neurons, a process called neurogenesis. The challenge is to prevent our neurons from dying in old age and keep growing new ones in order to stave off neurodegenerative diseases. Dr. Laurent’s research project aims - [Daiva Nielsen, PhD](https://www.bantingdiscoveryfoundation.ca/daiva-nielsen-phd/) - Department of Human NutritionMcGill University Characterization of the workplace food environment in Montreal Canada: New directions for gene-environment interaction and health research The retail food environment is acknowledged to play a significant role in public health and while previous studies have examined the role of the food environment around one’s residence, the food environment around - [Arneet Saltzman, PhD](https://www.bantingdiscoveryfoundation.ca/arneet-saltzman-phd/) - Department of Cell and Systems Biology University of Toronto Investigating the role of heterochromatin readers in genome stability Chromosomes consist of DNA packaged with proteins to form chromatin. The organization of our DNA into chromatin is important for controlling which genes are active or inactive, and for preserving the integrity of the genome during cell - [Imogen R Coe, PhD](https://www.bantingdiscoveryfoundation.ca/imogen-coe-2/) - Imogen Coe, Founding Dean of the Faculty of Science at Ryerson University, is internationally recognized for her research in the cell biology and biochemistry of membrane transport proteins. Dr Coe received a Banting Research Foundation grant in 1998, while at York University, to study the influence of steroid hormones on the uptake of a class - [Henry G Friesen, CC MD FRSC FCAHS](https://www.bantingdiscoveryfoundation.ca/henry-friesen/) - Henry Friesen is an internationally renowned endocrinologist best known for the discovery of human prolactin. Prolactin is a hormone that stimulates lactation in mammary glands and plays an important role in infertility and reproductive disorders. He was president of the former Medical Research Council of Canada from 1991 until 2000 when it became the Canadian - [Brenda L Gallie, CM MD FRCSC](https://www.bantingdiscoveryfoundation.ca/brenda-gallie/) - Brenda Gallie is a world-renowned ophthalmologist known for her contributions to the prevention, diagnosis and treatment of retinoblastoma, a childhood eye cancer. In 1983, shortly after being appointed assistant professor of ophthalmology at the University of Toronto, Dr Gallie received a Banting Research Foundation grant to study the mutations of retinoblastoma, a rare form of - [Charles H Hollenberg, OC MD FRSC](https://www.bantingdiscoveryfoundation.ca/charles-hollenberg/) - Charles Hollenberg was a physician, administrator, teacher and researcher. Born in Manitoba and educated at the University of Manitoba, he started his research career in 1960 at McGill University. After a decade there, he moved to the University of Toronto and became Chair of the Department of Medicine, where he transformed it into a place - [Mladen Vranic, OC MD DSc](https://www.bantingdiscoveryfoundation.ca/mladen-vranic/) - Mladen Vranic is best known for his work in glucose tracer methodology to study the effects of exercise and stress in diabetes. He came to Canada to work with Charles H Best, co-discoverer of insulin, and was first funded by the Banting Research Foundation in 1966 for his work on glucagon physiology. Glucagon plays a - [Updates from our 2017-2018 Discovery Awardees](https://www.bantingdiscoveryfoundation.ca/updates-from-our-2017-2018-discovery-awardees/) - [Welcome Gerald Lokash](https://www.bantingdiscoveryfoundation.ca/welcome-gerald-lokash/) ## Pages - [Home](https://www.bantingdiscoveryfoundation.ca/) - The first health science discovery catalyst in Canada Fueling innovative health research in Canada. We support early-career researchers and foster discoveries that significantly impact human health. - [Discovery Award Program](https://www.bantingdiscoveryfoundation.ca/discovery-award-program-2/) - Discovery Award Program The Banting Discovery Foundation provides feasibility and pilot grants of up to $30,000 to help early-career scientists establish independence and build their research programs. Funding supports essential research needs, from hiring trainees to acquiring equipment, enabling researchers to pursue bold ideas and advance health and biomedical science.The Discovery Award is highly competitive, - [2026 Discovery Awardees](https://www.bantingdiscoveryfoundation.ca/2026-discovery-award-winners/) - 2026 Discovery Award Winners Discovery Awardees since 1925 1374 The Banting Discovery Foundation is pleased to announce the 2026 Cohort of our Discovery Award winners. These twelve early-career scientists received a critical boost to pursue their research, that can one day transform lives. OUR 2026 WINNERS ARE: Michael Colacci Department of Medicine, University of Toronto - [About Us](https://www.bantingdiscoveryfoundation.ca/about-us/) - About Us Welcome to the Banting Discovery Foundation, a beacon of support for early career health researchers in Canada. Embark on a Bold New Journey of Discovery The Banting Discovery Foundation, is the oldest organization funding Health Research in Canada, founded in 1925. Our mission is to recognize and support Canada’s most talented and innovative - [Mitacs-Banting Postdoctoral Fellowship Program](https://www.bantingdiscoveryfoundation.ca/2026-2027-internship-application-guide/) - Mitacs and the Banting Discovery Foundation Partners for Innovation launch a call to address one of the following topics: (1) Precision Medicine (2) Designed Therapeutic & Diagnostic Approaches 2026-27 Internship Application Guide FRANÇAIS Mitacs: Established in 1999, Mitacs is a not-for-profit organization that fosters growth and innovation in Canada by solving business challenges with research - [Mitacs-Banting Postdoctoral Fellowship Program French](https://www.bantingdiscoveryfoundation.ca/2023-2024-internship-application-guide-fr/) - Mitacs et les partenaires pour l’innovation de la Fondation Découverte Banting lancent un appel de projets relevant de l’un des domaines suivants : (1) médecine de précision; (2)conception d’approches thérapeutiques et diagnostiques. Guide de demande de stage 2026-2027 ENGLISHMitacs:Créé en 1999, Mitacs est un organisme sans but lucratif qui favorise la croissance et l’innovation au Canada. - [2025 Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/2025-discovery-award-winners/) - 2025 Discovery Award Winners Below is the 100th cohort of the Discovery Award winners. These ten early-career scientists received an initial but critical boost to pursue their bold research that can transform lives one day. Discovery Awardees since 1925 1374 OUR 2025 WINNERS ARE: Jennifer Williams Assistant Professor, Faculty of Kinesiology and Physical Education, Wilfrid - [Our Leadership](https://www.bantingdiscoveryfoundation.ca/our-team/) - Banting Discovery Foundation Board of Directors Board of Directors John A. Campion Board Chair BA, JD (Toronto), Fellow-CIArb, Mediation (Harv), CS, Emeritus Bencher, EMBA ’22 (Rotman/Bocconi).Partner, Gardiner Roberts LLP Alain Beaudet, MD PhD Vice-Chair Former President, Canadian Institutes of Health Research Former President & CEO, Fonds de la recherche en santé du du Québec Borys Chabursky - [Annual Reports](https://www.bantingdiscoveryfoundation.ca/annual-reports/) - Annual Reports 2025 Annual Report 2024 Annual Report 2023 Annual Report 2022 Annual Report 2021 Annual Report 2020 Annual Report 2019 Annual Report 2018 Annual Report 2017 Annual Report 2016 Annual Report 2015 Annual Report 2014 Annual Report 2013 Annual Report 2012 Annual Report - [Case For Support](https://www.bantingdiscoveryfoundation.ca/case-for-support-2/) - Read our case for support Consultez notre soutenir notre cause THE FIRST HEALTH SCIENCE DISCOVERY CATALYST IN CANADA What if you had the chance to improve health, reduce human suffering, and build a better future for generations to come? What if we had nearly a century of evidence that this is possible, even amid escalating - [Timeline of Discovery](https://www.bantingdiscoveryfoundation.ca/discovery-timeline/) - The Timeline of Discovery 1929Petri dish growthMary L. Cowan Maitland was the first scientist to grow viruses in a petri dish.1939A future of safer milkHerbert Davenport Kay invented a test for pasteurized milk to help prevent the spread of tuberculosis.1948Advancing cervical screeningEva Waddell Mader MacDonald co-developed the rapid Pap test for cervical cancer screening.1957Knee injury - [Discovery Mentorship Program](https://www.bantingdiscoveryfoundation.ca/discovery-mentorship-program/) - Discovery Mentorship Program Great mentors focus on the whole person Click here to visit our College of Mentors Guiding Canada’s next generation of health innovatorsGroundbreaking research begins with bold ideas, and bold ideas need more than funding to thrive. The Discovery Mentorship Program is designed to give early-career researchers the tools, guidance, and connections they - [2024 Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/2024-discovery-award-winners/) - 2024 AWARD WINNERS Gregory Pearcey Assistant Professor, School of Human Kinetics and Recreation, Memorial University of Newfoundland Banting – Ontario Brain Institute Discovery Award Understanding How Our Brains Control Body Movements Dr. Pearcey received his PhD in neuroscience at the University of Victoria by study how our bodies move without thinking because of reflexes. Specifically, - [Research Funded](https://www.bantingdiscoveryfoundation.ca/research-funded/) - Brenda Gallie Professor Brenda L. Gallie, a leading expert in eye cancer research. She is dedicated to understanding and finding better ways to treat a rare childhood eye cancer called retinoblastoma. Through her groundbreaking work, Professor Gallie discovered that a specific gene called RB1 plays a critical role in causing these tumors. Her research has - [Contact Us](https://www.bantingdiscoveryfoundation.ca/contact/) - Contact us Banting Discovery Foundation PO Box 83524, Avenue Road PO Toronto ON M5R 3T6 info@bantingresearchfoundation.ca 416-595-9046 - [Our Mentors](https://www.bantingdiscoveryfoundation.ca/ourmentors/) - Our Mentors 2019 Awardee 2018 Awardee 2017 Awardee 2016 Awardee 2015 Awardee 2014 Awardee 2013 Awardee 2012 Awardee 2011 Awardee 2010 Awardee 2009 Awardee 2008 Awardee 2007 Awardee 2001 Awardee 2000 Awardee 1999 Awardee 1998 Awardee 1997 Awardee 1993 Awardee 1989 Awardee 1986 Awardee 1983 Awardee - [Celebrating 100 Years of The Banting Discovery Foundation](https://www.bantingdiscoveryfoundation.ca/celebrating-100-years-of-the-banting-discovery-foundation/) - Celebrating 100 Years of The Banting discovery foundation In 2025, the Banting Discovery Foundation proudly marks its 100th anniversary – a century of championing budding early-career scientists and bold biomedical discovery in Canada. To celebrate this remarkable milestone, the Foundation hosted a centennial event on May 29th, bringing together Banting Award winners from across the - [SOUTENIR NOTRE CAUSE](https://www.bantingdiscoveryfoundation.ca/case-for-support-fr/) - SOUTENIR NOTRE CAUSE Pourquoi cibler les chercheurs en début de carrière? Il est critique pour l’essor de notre économie et l’amélioration des soins de santé d’accroître nos investissements en recherche et développement. Le Canada forme chaque année une cohorte de jeunes chercheurs hautement qualifiés, dont l’apport est essentiel au développement de l’innovation. Or il peut - [Donate](https://www.bantingdiscoveryfoundation.ca/donate/) - Choose your donation options. Interac eTransfer, email ed@bantingresearchfoundation.ca Credit Card via CanadaHelps There are many ways you can support health science and biomedical discovery.All charitable gifts are eligible for a tax receipt according to Canada Revenue Agency guidelines.Please contact your legal representative or financial advisor for guidance or contact us directly to learn more. - [Discovery Award](https://www.bantingdiscoveryfoundation.ca/discovery-award-program/) - Meet the Discovery Awardees The Discovery Award Fueling Innovations in Health Science: The Discovery Award – Your Launchpad to Lifesaving Research Empower Your Research Journey The Discovery Award is your opportunity to ignite the flame of scientific breakthroughs. With financial support up to $30,000, propel your novel ideas into the realm of transformative health research. - [2023 Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/2023-discovery-award-winners/) - 2023 Discovery Award Winners The Banting Research Foundation is pleased to announce the Discovery Award winners for 2023 Discovery Awardees since 1925 1336 Advancing the Understanding of Macular Degeneration Sergio Crespo-Garcia, PhDUnraveling the Role of Folate Metabolism in Age-Related Macular Degeneration Read More About How Sergio is Pioneering Folate Metabolism Research for Age-Related Macular Degeneration - [What We Do](https://www.bantingdiscoveryfoundation.ca/what-we-do/) - Our Story Since 1925 Canada's First Catalyst for Health Science Discovery The Banting Research Foundation, named in honor of Frederick G. Banting, was founded on July 22, 1925, as a registered charity with a mission to fund health and biomedical research in Canada. Our inception followed the groundbreaking discovery of insulin by Sir Frederick Banting - [2022 Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/2022-discovery-award-winners/) - 2022 Discovery Award Winners The Banting Research Foundation is pleased to announce Discovery Award winners for 2022. Discovery Awardees since 1925 1356 Climate Change and Health: Spotlight Edward Ian Patterson, PhDExploiting insect-specific viruses to prevent transmission of arthropod-borne viruses Read more about the impact that Professor Patterson's research will have on climate and health challenges - [Discovery Mentorship Open House Program](https://www.bantingdiscoveryfoundation.ca/discovery-mentorship-program/discovery-mentorship-open-house-program/) - [Program Schedule](https://www.bantingdiscoveryfoundation.ca/mentorship-open-house-program-schedule/) - Program Schedule - [News](https://www.bantingdiscoveryfoundation.ca/news-stories/) - Latest News and Stories Banting Discovery Foundation 2026 Award Winners Toronto, June 16, 2026 – The Banting Discovery Foundation is pleased to announce this year’s Discovery Award winners: Megan Beggs (College of Pharmacy and Nutrition, Read More » June 16, 2026 No Comments The Banting Discovery Foundation Announces its 100th Cohort of Award Winners Banting Discovery - [Chair's Message](https://www.bantingdiscoveryfoundation.ca/chairs-message/) - Message from the Chair Our Foundation was launched almost 100 years ago to sustain support for Sir Frederick Banting’s legacy of creative research that led to the discovery of insulin. Banting’s story is quite inspiring because with very little seed funding and just enough resources to carry out a limited number of experiments, along with Charles Best, - [Videos & Media](https://www.bantingdiscoveryfoundation.ca/videos/) - Videos & Media Videos Banting Research Foundation 23 Videos 2022 Discovery Awardee Bios Edward Ian Patterson, PhD Mihai Duduta, PhD Kimberly Dunham-Snary, PhD Amy Huei-Yi Lee, PhD Silvia Pozzi, PhD Event Recap 2022 Discovery | Bold Ideas to Tackle Health and Climate Change Challenges 2021 Discovery Awardee Announcement 2021 Mentorship Symposium 2020 Discovery Awardee Gala - [Home](https://www.bantingdiscoveryfoundation.ca/banting-research-foundation-2/) - Advancing Cancer Research: Dr. Jeffrey Leyton's Novel Approaches to Targeted TherapyDiscover how Dr. Jeffrey Leyton's groundbreaking research is revolutionizing cancer treatment, with a focus on developing probes to accurately detect and treat muscle invasive bladder cancer.Learn moreThe Link Between Exercise and Memory: New Research ExplainedMatthieu Boisgontier, a Banting Discovery awardee, led the strongest case to - [The Banting Research Foundation Member Handbook](https://www.bantingdiscoveryfoundation.ca/handbook/) - [2021 Discovery Award Application](https://www.bantingdiscoveryfoundation.ca/2021-discovery-award-application/) - [Guide de demande de stage 2022-2023](https://www.bantingdiscoveryfoundation.ca/guide-de-demande-de-stage-2022-2023/) - English Mitacs et la Fondation de recherche BantingPartenaires en innovation face aux changements climatiques à la santé et à l’équité Mitacs Créé en 1999, Mitacs est un organisme sans but lucratif qui favorise la croissance et l’innovation au Canada. En partenariat avec les meilleurs établissements d’enseignement au pays et dans le monde, nous résolvons des - [Partners](https://www.bantingdiscoveryfoundation.ca/partners/) - Our Partners include: J.P. Bickell Foundation - [Chair's Message](https://www.bantingdiscoveryfoundation.ca/what-we-do/chairs-message/) - Chair's Message Our Foundation was launched almost 100 years ago to sustain support for Sir Frederick Banting’s legacy of creative research that led to the discovery of insulin. Banting’s story is quite inspiring because with very little pilot funding and just enough resource to carry out a limited number of experiments he, along with Best, - [2020 Grant Review Panel](https://www.bantingdiscoveryfoundation.ca/review-panel/) - The Banting Research Foundation is deeply grateful to all its panelists for voluntarily contributing each year their time, expertise and wisdom to the vital task of reviewing grant applications. The Grant Review Panel’s commitment to selecting the very best applicants and most innovative of the projects proposed is fundamental to the Foundation’s purpose. 2020 Grant - [Join our community!](https://www.bantingdiscoveryfoundation.ca/subscribe/) - Subscribe to our quarterly newsletter to stay up to date on grant deadlines, our research funded, events, and more! * indicates required Email Address * First Name Last Name - [Notable Alumni](https://www.bantingdiscoveryfoundation.ca/notable-alumni/) - Janet Rossant, CC PhD FRS FRSC1983 Award RecipientWorld-renowned expert in developmental biology Read More Charles Hollenburg, OC MD FRSC1965 Award RecipientA leader of the Canadian medical communityRead More Henry G Friesen, CC MD FRSC FCAHS1966 Award RecipientBest known for the discovery of human prolactinRead More Mladen Vranic, OC MD DSc1966 Award RecipientPioneer in metabolic physiology, ## Sliders - [](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/8516/) - The Banting Foundation is very grateful for the kind support of the Heffel Fine Art auction in the selling of two landscape paintings by Sir Frederick Banting. The auction on November 24, 2022 raised funds in support of our Discovery Award program for early career biomedical investigators. Heffel Fine Art Auction graciously donated their professional - [Discovery 2022](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/discovery-2022/) - Bold Ideas to Tackle Health Challenges and Climate Change Health Impacts was a successful event. Our moderator Ivan Semeniuk was terrific, and our panelists were thoughtful and inspiring. The conversation highlighted the diversity of research, impact and ongoing challenges we all face. Stay tuned for the sequel. - [NEW Mitacs-Banting Discovery Post-Doc Awards](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/mitacs-banting-discovery-post-doc-scholars-award/) - Mitacs and Banting Research Foundation are partners on Innovation to Address Climate Change, Health and Equity. We celebrate this with a new Discovery Postdoctoral Scholars Program, which will support the brightest postdoctoral scholars conducting biomedical sciences research to address health inequities – under the supervision of faculty/early career researchers who are previous Banting Research Foundation - [The 2021 Discovery Award Winners are all here. Find out more](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/the-2021-discovery-award-winners-are-all-here-find-out-more/) - [2021 Discovery Award Winners](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/2021-discovery-awards/) - Learn more about their research...watch the interviews - [Mitacs-Banting Discovery Awards](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/mitacs-banting-discovery-awards/) - The Banting Research Foundation is very pleased to announce a new partnership with Mitacs that will double the number of Discovery Awards for the coming year. Six emerging biomedical researchers will receive the new Mitacs-Banting Discovery Award, valued at $25,000 each. The Co-funded Discovery Awards reflect the shared commitment of Mitacs and the Banting Research - [100 Years of Insulin](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/whats-happening-this-month-dr-bantings-birthday-nov-14/) - Stories on what the discovery can teach us about one of the most widespread health crises of our time. U of T Med Magazine 100 Years of Insulin: stories on current research, news and events on this year-long celebration. Events line up here - [The Discovery Award 2020 winners are all here!](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/the-discovery-awards-2020-winners-are-all-here/) - [Investing in the Future](https://www.bantingdiscoveryfoundation.ca/xt_theme_slider/lets-build-the-next-banting/) - Help support the early careers of outstanding health and biomedical researchers in Canada ## Testimonials - [Florian Bentzinger](https://www.bantingdiscoveryfoundation.ca/xt_testimonial/linux-wlis/) - Owing to the generous Banting Discovery Award we where able to significantly advance our research program. - [Janet Rossant](https://www.bantingdiscoveryfoundation.ca/xt_testimonial/taylor-swift/) - Early support of the Foundation was very helpful in setting my course towards the Gairdner Wightman award. - [Imogen Coe](https://www.bantingdiscoveryfoundation.ca/xt_testimonial/mr-donald/) - Assistance from my award helped me on my path to becoming the advocate, scientist, and academic leader I am today. - [Christopher Dennison](https://www.bantingdiscoveryfoundation.ca/xt_testimonial/john-doe/) - Please accept our sincere thanks and trust that these funds were central in advancing our work on head protection. - [Tara Moriarty](https://www.bantingdiscoveryfoundation.ca/xt_testimonial/sunny/) - [the grant] was essential to the survival and development of my research lab at a very difficult time of funding ... - [Jennifer Gordon](https://www.bantingdiscoveryfoundation.ca/xt_testimonial/taylor/) - Success begets success so smaller grants like the Discovery Award can make a big difference to early career investigators ... ## Volunteers - [Luka Milosevic, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/luka-milosevic-phd/) - [Amy Huei-Yi Lee, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/amy-huei-yi-lee-phd/) - [Kimberly Dunham-Snary, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/kimberly-dunham-snary-phd/) - [Silvia Pozzi, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/silvia-pozzi-phd/) - [Mihai Duduta, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/mihai-duduta-phd/) - [Edward Ian Patterson, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/edward-ian-patterson-phd/) - [Catharine Whiteside](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/catharine-whiteside-2/) - Emerita Professor and Former Dean of Medicine, University of Toronto. - [Shanon Grauer](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/shanon-grauer/) - Counsel, INQ Law; Retired senior partner, McCarthy Tétrault LLP; Adjunct Professor, Institute of Health Policy, Management and Evaluation, University of Toronto - [Alain Beaudet](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/alain-beaudet/) - Dr. Alain Beaudet is the Past-President of the Canadian Institutes of Health Research (CIHR), Canada’s premier health research funding agency. In this role, Alain pioneered a far-reaching Patient-oriented Research Strategy and increased CIHR’s involvement in global health research, namely through its participation in the Global Alliance for Chronic Disease (GACD), an international organization which he - [Andrea Donlan](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/andrea-donlan/) - Andrea Donlan is a strategic communications consultant bringing more than 20 years’ experience in developing, managing and implementing organizational positioning strategies for Canada’s leading players in the public, private and non-profit sectors. An expert on corporate citizenship, she works with companies to explore how they can harness their values to address some of the most pressing - [André Morriseau](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/andre-morriseau/) - André Morriseau (Fort William First Nation) is an enthusiastic advocate and ambassador for Indigenous arts, culture and public affairs. Former Secretariat for the National Aboriginal Achievement Foundation (NAAF) now Indspire, Communications Officer for the Chiefs of Ontario (COO). He is the former Chair of the James Bartleman Aboriginal Youth Creative Writing Awards Jury, Ontario Arts - [Sheelagh Whittaker](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/sheelagh-whittaker/) - As the first female CEO of a company listed on the Toronto Stock Exchange (Canadian Satellite Communications Inc.), Sheelagh jokes that her meme is that of a professional breath of fresh air. From her early days with The Canada Consulting Group (now Boston Consulting), followed by the tremendous satisfaction of winning the license for CBC - [Gerald Lokash](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/rocky/) - C.A./Chartered Professional Accountant and Business Advisor (Retired) - [Donald Guloien](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/john-doe/) - Founder of Guloien Capital. Past President and CEO Manulife Financial - [Sagi Abelson, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/sagi-abelson-phd/) - Computational Biology, Ontario Institute for Cancer Research - Exploring the blood of cancer patients at the single-cell level Single-cell technologies are rapidly advancing our knowledge about how different cells in our body function. His research leverages large, publicly available single-cell datasets to build a comprehensive single-cell classifier. This classifier will then be used to detect impending - [Matthieu P. Boisgontier, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/matthieu-p-boisgontier-phd/) - Rehabilitation Sciences, University of Ottawa - Retraining the automatic reaction to physical activity and sedentary stimuli in geriatric patients Most individuals are aware of the benefits to health of regular physical activity and have good intentions to exercise. Yet, 1.4 billion people worldwide are inactive, which suggests that turning intention into action can be challenging. His research - [Angela C. Cheung, MD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/angela-c-cheung-md/) - Clinical Epidemiology Program, The Ottawa Hospital Research Institute - Machine Learning in HCC Liver cancer is the 6th most common cancer in the world, and the 3rd most common cause of death from cancer. Her work uses artificial intelligence to fight liver cancer by training computers to recognize it using images from patients with or - [Owais Khan, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/owais-khan-phd/) - Electrical, Computer & Biomedical Engineering, Ryerson University - Healing Broken Hearts with Computer Simulations Coronary artery disease is the #1 killer globally. Coronary arteries supply heart muscles with oxygenated blood. Due to various risk factors, these arteries can become clogged, called stenosis, and reduce oxygen supply to heart muscles, which leads to lethal heart attacks. - [Alanna Weisman, MD, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/alanna-weisman-md-phd/) - Department of Medicine, University of Toronto - Impact of socioeconomic factors on insulin pump use in type 1 diabetes Insulin pumps are one method of insulin treatment for people with type 1 diabetes and insulin pumps have a number of advantages. Although the Ontario government provides funding for all individuals with type 1 diabetes to use - [Glen McGee, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/glen-mcgee-phd/) - Statistics and Actuarial Science, University of Waterloo - Addressing Informative Presence Bias in Analyses of Electronic Health Records Medical researchers frequently investigate relationships between complex diseases like autism spectrum disorder and other potentially related conditions. He will develop statistical tools to correct the bias that exists in examinations of autism patients due to the fact - [J. Patrick Murphy, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/j-patrick-murphy-phd/) - Biology, University of Prince Edward Island - Exploring an alternative approach to targeting serine biosynthesis-dependent cancers The use of nutrients like glucose is tuned up by cancer cells for rapid growth. One example of how glucose is used differently by some cancers is the production of a common amino acid, serine. This supports cell growth - [Andrew A. Nicholson, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/andrew-a-nicholson-phd/) - Psychiatry & Behavourial Sciences, McMaster University - Regulating Neural Connectivity in Post-traumatic Stress Disorder with Real-time Neuroimaging Exposure to traumatic events can result in the development of post-traumatic stress disorder (PTSD), a highly debilitating psychiatric illness. Despite the high prevalence of PTSD world-wide, approximately 40% of individuals have been shown to be treatment resistant to - [Heather Prime, C. Psych](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/heather-prime-c-psych/) - Psychology, York University - A Family Recovery Program to Support Child Mental Health During and After COVID-19 The COVID-19 pandemic has led to an increase in children’s mental health problems, which may have lasting implications for their physical and mental health as adults. This is due to the social impact of the pandemic on family - [Holly Sparks, DVM, PhD, DACVS-LA](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/holly-sparks-dvm-phd-dacvs-la/) - Veterinary Clinical & Diagnostic Sciences, University of Calgary - Establishing Non-invasive Diagnostic Criteria for Tissue Pathology in Tendinopathy Tendinopathy remains a common and debilitating condition in human and veterinary medicine alike. When identified early in the spectrum of disease, tendon damage is reversible and severe injury may be prevented. Her work will develop non-invasive diagnostic - [Nicole Templeman, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/nicole-templeman-phd/) - Biology, University of Victoria - Limiting insulin levels to enhance egg cell quality and female fertility during aging A declining female reproductive capacity (signified by rising rates of infertility, birth defects, and miscarriage) is one of the first signs of aging, and is linked to deteriorating quality of egg cells. Her project will use a mouse - [Kim Tsoi, MD, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/kim-tsoi-md-phd/) - Lunenfeld-Tanenbaum Research Institute, Sinai Health System - Development of a Nanoparticle-Based Approach to Treat Lung Metastases in Soft Tissue Sarcoma Soft tissue sarcomas (STS) are a rare, aggressive type of cancer that arises from connective tissue. While the primary tumour is controlled with radiation and surgery, half of patients develop metastases and are incurable. Sarcomas are - [Reinhart Reithmeier](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/reinhart-reithmeier/) - Professor, Department of Biochemistry, University of Toronto. Chair, Royal Canadian Institute of Science. - [Stephen Scherer](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/stephen-scherer/) - Chief of Research, and Director of The Centre for Applied Genomics, Hospital for Sick Children, and University of Toronto McLaughlin Centre - [Richard Nunn](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/richard-nunn/) - Senior Client Service Partner, Financial Services, Deloitte - [John S. Floras](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/john-s-floras/) - Professor, Faculty of Medicine, University of Toronto. Deputy Physician-in-Chief, Research, Mount Sinai Hospital - [Frederick H. Lowy](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/frederick-lowy/) - Member, Pierre Elliott Trudeau Foundation Former President and Vice Chancellor, Concordia University Emeritus Professor and Former Dean of Medicine, University of Toronto - [Maurine Kwok](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/maurine-kwok/) - Maurine is a highly respected value creator within the business community and her wealth of project management and regulatory experience spans the globe. Prior to joining the Banting Research Foundation she was director of a global integrative health company. In this leadership role she partnered with CEOs, senior executives, entrepreneurs and local communities to transform - [Malika Oubaha, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/malika-ouhaba-phd-2/) - Department of Biological Sciences, University of Quebec at Montreal – Premature Aging of Blood Vessels in Eye Diseases Quality of life is adversely affected by visual impairment or loss of sight – commonly caused by retinal vascular diseases. We have recently discovered premature aging in blood vessels during retinopathy. We aim to identify the molecular - [Lindsay Cahill, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/lindsay-cahill-phd/) - Department of Chemistry, Memorial University of Newfoundland – Understanding the Effects of Treatment to Prevent Brain Injury in Premature Babies One of the most common pregnancy complications is giving birth too early. In Canada, 8% of babies are born premature and while survival rates have improved dramatically, the risk of severe disability from brain injury - [Jennifer Geddes-McAlister, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jennifer-geddes-mcalister-phd-2/) - Department of Molecular and Cellular Biology, University of Guelph – Combatting Fungal Infections through the Discovery and Mechanistic Elucidation of Novel Anti-virulence Strategies Fungal pathogens are emerging as critical threats to global health, with over 300 million people affected by serious fungal diseases worldwide. In Canada, pathogenic fungi are a growing public health concern with - [Kate Weinberger, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/kate-weinberger-phd/) - School of Population and Public Health, Faculty of Medicine, University of British Columbia – Heat Waves and Child Health in a Warming World Major heat waves have resulted in large, immediate increases in illnesses and deaths. For example, in Vancouver, a 2009 heat wave led to more than 100 deaths over a period of several - [Chantelle Capicciotti, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/chantelle-capicciotti-phd/) - Departments of Chemistry and Biomedical and Molecular Sciences, School of Medicine, Queen’s University - Harnessing Cell-Surface Glyco-Engineering to Enhance Stem-Cell Therapies Stem cell therapies are promising treatments for various infections and diseases. To be effective, stem cells must be delivered to specific tissue such as bone marrow. Unfortunately, many stem cells lack the required carbohydrates - [Dylan Kobsar, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/dylan-kobsar-phd-1/) - Department of Kinesiology, McMaster University – Stepping Out of the Lab: New methods to translate movement analyses into the real-world with wearable sensor Osteoarthritis is a degenerative joint disease characterized by the loss of cartilage and change in bone – resulting in pain, disability, and a reduced quality of life for millions of Canadians. Wearable - [Che Colpitts, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/che-colpitts-phd-1/) - Department of Biomedical and Molecular Sciences, School of Medicine, Queen’s University – Membrane Re-modelling as an Antiviral Target for Coronaviruses The recent outbreak of coronavirus in Wuhan, China, underscored the severe health and societal impact of emerging viruses. There are no approved antivirals for coronaviruses or other emerging viruses. To mitigate this global health threat: - [Dylan Kobsar, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/dylan-kobsar-phd/) - Department of Kinesiology, McMaster University – Stepping Out of the Lab: New methods to translate movement analyses into the real-world with wearable sensor Osteoarthritis is a degenerative joint disease characterized by the loss of cartilage and change in bone – resulting in pain, disability, and a reduced quality of life for millions of Canadians. Wearable - [Cindi M. Morshead](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/cindi-m-morshead/) - Professor and Chair, Division of Anatomy and Department of Surgery Rehabilitation Sciences Institute, Institute of Biomaterials and Biomedical Engineering, Toronto Rehabilitation Institute, The Donnelly Centre at the University of Toronto - [Molly Verrier](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/erik-ban/) - Associate Professor Emeritus, Former Chair of Physical Therapy and Rehabilitation Science, University of Toronto - [Salim Islam, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/salim-islam-phd/) - Department of Microbiology and Biotechnology, INRS – Institut Armand-Frappier - Understanding colonization and persistence in bacterial social networking Bacteria can colonize both living and non-living surfaces, leading to the development of a microbial community. However, the manner in which different types of bacterial cells interact with each other in such densely-populated zones is poorly understood. - [Nicholas Strzalkowski, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/nicholas-strzalkowski-phd/) - Department of Biology, Mount Royal University - Sensory Feedback in Dystonia Muscle sensory feedback is thought to contribute to dystonia, however this has not been investigated directly. Dr. Strzalkowski's research group believes that abnormal sensory feedback from specialized muscle receptors contributes to the involuntary dystonic muscle contractions and is associated with botulinum toxin treatment outcomes. - [Lindsay Bodell, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/lindsay-bodell-phd/) - Department of Psychology, Western University - Negative Affect and Reward Processing in Individuals with Binge Eating Binge eating is defined by consuming a large amount of food over a short time period and feeling out of control while eating. This behavior is a key feature of eating disorders, affects approximately 10% of the population, and - [Jonathan Perreault, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jonathan-perreault-phd/) - INRS - Institut Armand Frappier - Regulation in the opportunistic pathogen Burkholderia by the MAEB RNA motif Aside from their role in storing hereditary information, DNA and RNA are now known to have many more functions. Living organisms have a plethora of RNAs that control numerous processes in cells. One such RNA, named MAEB, was - [Takako Niikura, DVM PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/takako-niikura-dvm-phd/) - Faculty of Health Sciences, Simon Fraser University - Regulation of amyloid beta metabolism In Alzheimer's disease (AD), progressive brain atrophy and dementia appear because of neuronal cell death and synaptic dysfunction in brains. Amyloid beta plays a central toxic role in AD pathogenesis. Combination of the direct suppression of neuronal death and removal of amyloid - [Tara Moriarty, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/tara-moriarty-phd/) - Matrix Dynamics Group, Faculty of Dentistry, University of Toronto - Vascular adhesion mechanisms of the Lyme disease spirochete Blood-borne spread (dissemination) of pathogens is a critical step in the development of serious infectious disease, and is responsible for most of the mortality due to bacterial infection. The dissemination mechanisms of many bacterial pathogens are largely - [Simon Lees, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/simon-lees-phd/) - Faculty of Medicine, Lakehead University - The IL-6 paradox in the development of insulin resistance Paradoxically, elevated IL-6 is associated with insulin resistance and type 2 diabetes, while at the same time strong evidence supports the notion that IL-6 may facilitate improved insulin signaling as a result of physical activity. The proposed research will determine - [Marcelo Berlim, MD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/marcelo-berlim-md/) - Department of Psychiatry, McGill University - Remediating decision-making deficits in depressed subjects at high risk for suicide with transcranial magnetic stimulation We aim to assess whether high frequency repetitive transcranial magnetic stimulation, a safe and non-invasive method for modulating the activity of specific brain regions, when applied over the left region of the forehead (ie, - [Michelle Scott, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/michelle-scott-phd/) - Department of Biochemistry, Université de Sherbrooke - Characterization of a novel function of small RNAs in alternative splicing The process of alternative splicing allows the production of multiple distinct proteins from a single gene, in a manner that can be cell-type specific. Alternative splicing requires an extensive and complex regulation. Diverse human diseases can be - [Martin Lévesque, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/martin-levesque-phd/) - Department of Psychiatry and Neurosciences, Université Laval - Molecular mechanisms of axon guidance mediated by PlexinC1 in dopamine neuron axonal projections Degeneration of midbrain dopaminergic neurons (mDA) is the principal cause of Parkinson's disease. Grafts of dopaminergic neurons newly generated from stem cells represent a promising therapeutic avenue. However, inappropriate re-innervation of the grafted neurons - [Dennis Jensen, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/dennis-jensen-phd/) - Department of Kinesiology & Physical Education, McGill University - Physiological mechanisms of dyspnea relief and improved exercise tolerance after treatment with oral morphine in patients with advanced chronic obstructive pulmonary disease (COPD) Chronic obstructive pulmonary disease (COPD) is a progressive disease of the lungs and airways, causing shortness of breath (dyspnea) and exercise intolerance. Conventional - [Carl Ernst, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/carl-ernst-phd/) - Department of Psychiatry, McGill University - Functional analysis of the 16p11.2 locus using patient-derived induced-pluripotent stem cells Large deletions of DNA on chromosome 16 are associated with Autism Spectrum Disorders (ASD) in about 1% of all Canadians with autism, and many more Canadians with intellectual disability. I have recruited and clinically assessed two independent families - [Alexandre Douplik, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/alexandre-douplik-phd/) - Physics Department, Ryerson University - Surface-enhanced Raman fiber sensor for endoscopic early detection of tumor-related biomolecules in gastroenterology The goal of the project is development of surface-enhanced Raman spectroscopy fiber probes for high sensitive and rapid non-invasive diagnostics including malignancy detection. Optical sampling of biological molecules can detect specific Raman "fingerprints" including cancer "signatures" with - [Marie-Ève Tremblay, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/marie-eve-tremblay-phd/) - Département de médecine moléculaire, Université Laval - Microglial relationships with synaptic elements in Alzheimer's disease A series of recent discoveries have challenged our view of microglia, the brain immune cells, showing unexpected roles in the active maintenance of neuronal circuits throughout the lifespan. Contributing to this nascent field of investigation, this project aims at exploring - [Dave Richard, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/dave-richard-phd/) - Département de microbiologie-infectiologie et d'immunologie, Université Laval - Protein trafficking to the apical complex of the malaria parasite Malaria is one of the world's most common infectious diseases, with approximately 274 million cases each year and 1 million deaths, and thus represents one of the most devastating global public health problems. The lack of an - [Pierre-Yves Lozach, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/pierre-yves-lozach-phd/) - Centre INRS – Institut Armand-Frappier Bunyavirus entry into mammalian cells Bunyaviridae is a large family of viruses mainly transmitted by arthropods such as mosquitos and ticks. Many bunyaviruses are important pathogens in humans and livestock. Due to their mode of transmission, they are considered emerging agents of diseases. Unfortunately, bunyaviruses are understudied, which has contributed - [Margaret K Hahn, MD PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/margaret-k-hahn-md-phd/) - Centre for Addiction and Mental Health - Central insulin to prevent olanzapine-induced adiposity: a rodent model Atypical antipsychotic (AAP) medications, the mainstay treatment for psychosis and schizophrenia, are defined by weight gain and metabolic problems that likely contribute to a 2-fold increase in cardiovascular (CV) deaths in this population. Lifestyle interventions often have limited success, - [David Chatenet, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/david-chatenet-phd/) - Centre INRS–Institut Armand-Frappier - Design and synthesis of peptide inhibitors of PqsE as novel antibacterial therapeutics Pseudomonas aeruginosa (Pa), a prevalent opportunistic human pathogen responsible for morbidity and mortality among individuals suffering from cystic fibrosis, is notorious for its high resistance to antibiotic treatments. As recently demonstrated, cell-to-cell signaling regulated by the PqsE enzyme plays - [Craig Bailey, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/craig-bailey-phd/) - Department of Biomedical Sciences, University of Guelph - Nicotinic receptor signaling in a mouse model of Fetal Alcohol Spectrum Disorder Chronic prenatal exposure to alcohol can produce a spectrum of adverse effects known collectively as Fetal Alcohol Spectrum Disorder (FASD). Although deficits in attention rank among the most common and persistent components of FASD, mechanisms - [Emanuel Rosonina, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/emanuel-rosonina-phd/) - Department of Biology, York University - Regulation of transcription and splicing factors by sumoylation SUMO is a protein modification that plays important roles in regulating many cellular processes. Several proteins that are involved in neurodegenerative disease are modified by SUMO, and abnormal protein modifications by SUMO have been implicated in many types of cancer, indicating - [Ewa Niechwiej-Szwedo, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/ewa-niechwiej-szwedo-phd/) - Department of Kinesiology, University of Waterloo - The role of binocular vision in the development of fine motor skills Seeing in depth is essential for guiding purposeful movements, such as reaching and grasping for toys or food, catching a ball or using tools to accomplish complex tasks. Binocular vision provides important cues for 3D depth - [Benoît Arsenault, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/benoit-arsenault-phd/) - Department of Medicine, Université Laval - Impact of a lifestyle modification program on high-density lipoprotein function Plasma levels of high-density lipoprotein (HDL) cholesterol, often referred to as “the good cholesterol”, are inversely associated with cardiovascular disease and type 2 diabetes risk. Several lines of evidence suggest that these associations could be explained by the fact - [Yannick Doyon, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/yannick-doyon-phd/) - Department of Molecular Medicine, Université Laval - In vivo genome editing as a novel class of human therapeutics to treat pediatric metabolic disorders Genetic disorders in children are individually rare but collectively frequent, affecting the lives of approximately 500,000 children in Canada. They often are serious, life threatening or fatal, but because each rare disease - [Jennifer Heisz, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jennifer-heisz-phd/) - Department of Kinesiology, McMaster University - Examining the dose-response relationship between physical exercise and cognitive function in older adults Alzheimer's disease is the most common form of dementia, causing severe cognitive impairment and interfering with daily life. As the population ages, the number of Canadians living with dementia is projected to double within a generation - [Jeffrey Leyton, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jeffrey-leyton-phd/) - Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke - An advanced development in targeted radiation against muscle invasive migrating bladder cancer cells Bladder cancer affects thousands of Canadians on an annual basis. Unfortunately, bladder cancer remains one of the most difficult cancers to manage. The treatment options currently available to patients with muscle invasive - [Jeffrey Chen, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jeffrey-chen-phd/) - VIDO-InterVac, University of Saskatchewan - Towards a next generation of superior BCG tuberculosis vaccines Tuberculosis is a serious global health problem, with one-third of the world’s population having been infected by the infectious agent, Mycobacterium tuberculosis. The only available tuberculosis vaccine, live M. bovis BCG vaccine, has an excellent record in protecting infants, but works - [Jeremy Hirota, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jeremy-hirota-phd/) - Department of Medicine University of British Columbia - A 3D-printed human airway model for studying respiratory mucosal immune responses Exposure to allergens and air pollutants in the air we breathe can lead to “lung attacks” in individuals with lung diseases, but it is unclear how this happens and what we can do to stop it. - [Petra Kienesberger, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/petra-kienesberger-phd/) - Department of Biochemistry and Molecular Biology Dalhousie University - Role of the adipokine autotaxin in obesity-associated insulin resistance Insulin resistance, a major complication of obesity, is a condition where tissues such as skeletal muscle become unresponsive to the blood sugar-lowering hormone insulin. Insulin resistance can lead to type 2 diabetes, which is associated with a - [Morgan Langille, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/morgan-langille-phd/) - Department of Pharmacology Dalhousie University - Design and implementation of a human microbiome interaction database It is becoming increasingly apparent that the microbes living on and in our bodies, called the human microbiome, are important for human health. These microbes help with the digestion of food, defend against unwanted pathogens, stimulate and keep our immune - [Joon Lee, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/joon-lee-phd/) - School of Public Health and Health Systems University of Waterloo - Personalized predictive analytics based on electronic medical data and patient similarity metrics As hospitals and doctors’ offices in Canada rapidly adopt electronic medical records (EMRs), the enormous clinical value of ever-increasing EMR data is receiving the spotlight. In particular, massive EMR data can facilitate - [Catherine Martel, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/catherine-martel-phd/) - Department of Medicine Université de Montréal/ Montreal Heart Institute Research Centre - Lymphatic vessel function in atherosclerosis High blood cholesterol is an important risk factor for cardiovascular diseases such as atherosclerosis. High-density lipoprotein (HDL) is called "good cholesterol" because it transports cholesterol away from tissues, such as the blood vessel walls, carrying cholesterol through the - [Michael Suits, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/michael-suits-phd/) - Department of Chemistry and Biochemistry Wilfrid Laurier University - Protein structure-function relationships in periodontal disease In the mouth, a wide variety of microorganisms are embedded in biofilms that contribute to periodontal diseases such as gum disease and tooth decay. To understand the contribution of a consortium of periodontal pathogens, including Porphyromonas gingivalis, Tannerella forsythia, and - [Roxane Paulin, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/roxane-paulin-phd/) - Department of Medicine, Université Laval - Targeting ErbB2 by TAK-165 reverses pulmonary hypertension in vitro and in vivo In pulmonary hypertension (high blood pressure in the lungs), cells forming the walls of arteries in the lungs proliferate like cancer cells, narrowing the arteries and making it difficult for blood to pass through. There is also - [Noam Miller, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/noam-miller-phd/) - Department of Psychology, Wilfrid Laurier University - Exploring neural mechanisms of social behavior using zebrafish This research study uses zebrafish, a small freshwater species of fish commonly used in genetic and developmental research, to explore the mechanisms of social behavior. Zebrafish spend the majority of their time in groups and have complex social interactions, including - [Kaitlyn McLachlan, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/kaitlyn-mclachlan-phd/) - Department of Psychology, University of Guelph - Evaluating novel neurobiomarkers in the identification of adults with FASD using portable eye tracking and EEG technology Individuals with fetal alcohol spectrum disorder (FASD) are overrepresented in the criminal justice system. There is an urgent need to identify neurobiomarkers of FASD and individuals at risk in order to - [Jeffrey Gagnon, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jeffrey-gagnon-phd/) - Department of Biology, Laurentian University - Investigating the role of H2S in the regulation of ghrelin secretion Ghrelin, a hormone produced in the endocrine cells of the stomach, regulates several aspects of metabolic health, including appetite and energy storage. Recently, meals high in the amino acid cysteine have been shown to reduce ghrelin secretion. Foods - [Christopher Dennison, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/christopher-dennison-phd/) - Department of Mechanical Engineering, University of Alberta - Impact severity metric for focal head and diffuse brain injury Whether or not today’s helmets protect the wearer from mild diffuse brain injuries, sometimes referred to as concussions, is the topic of intense debate. One of the primary venues for this debate is in the helmet standards - [Jeanette Boudreau, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jeanette-boudreau-phd/) - Department of Microbiology and Immunology, Dalhousie University - Directing natural killer cell cytotoxicity to the tumour’s susceptibilities Natural killer (NK) cells are white blood cells that kill tumours. The potential of each NK cell to kill tumours is counterbalanced by its ability to be inhibited by healthy cells through its inhibitory receptors. Dr Boudreau aims - [Arneet Saltzman, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/arneet-saltzman-phd/) - Department of Cell and Systems Biology, University of Toronto - Investigating the role of heterochromatin readers in genome stability Chromosomes consist of DNA packaged with proteins to form chromatin. The organization of our DNA into chromatin is important for controlling which genes are active or inactive, and for preserving the integrity of the genome during - [Daiva Nielsen, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/daiva-nielsen-phd/) - Department of Human Nutrition, McGill University - Characterization of the workplace food environment in Montreal Canada: New directions for gene-environment interaction and health research The retail food environment is acknowledged to play a significant role in public health and while previous studies have examined the role of the food environment around one’s residence, the food - [Benoit Laurent, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/benoit-laurent-phd/) - Department of Biochemistry, Université de Sherbrooke - Deciphering the epigenetic regulation of alternative splicing in neurons Aging can reduce the birth of new neurons, a process called neurogenesis. The challenge is to prevent our neurons from dying in old age and keep growing new ones in order to stave off neurodegenerative diseases. Dr. Laurent's research - [Mahsa Jessri, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/mahsa-jessri-phd/) - Department of Food, Nutrition, and Health, University of British Columbia - Dietary Patterns and Food Policies: Measuring the Impact on Health With the dramatic increase in life expectancy that occurred during the 20th century, we can be more optimistic than ever that good health is both achievable and sustainable. Unlike smoking, whose contribution to death - [Andrea Bombak, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/andrea-bombak-phd/) - Department of Sociology, University of New Brunswick - Intersections of Weight Stigma in New Brunswick Weight stigma affects risk for stress, diabetes, and heart disease. Little research has explored how people facing other stigmas (like racism, ageism, or classism) are affected by weight stigma. Place also affects health by making it easier or more difficult - [Jennifer Gordon, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/jennifer-gordon-phd/) - Department of Psychology, University of Regina - HPA axis dysregulation in the etiology of perimenopausal depression Women are 2-4 times more likely to develop depression during perimenopause, the menopause transition phase, than at any other time in their lives. Dr Gordon proposes that increased estrogen fluctuation during this phase may trigger dysregulation of the hypothalamic-pituitary-adrenal - [Gareth Lim, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/gareth-lim-phd/) - CRCHUM, Department of Medicine, Université de Montréal - Evaluating the therapeutic potential of 14-3-3ζ for the treatment of obesity Approximately 25% of Canadians are either overweight or obese. Current therapies have only modest success in reducing body weight, and surprisingly, none directly target fat cells, which are key in the development of obesity. Fat cells - [Florian Bentzinger, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/florian-bentzinger-phd/) - Department of Pharmacology-Physiology, Universite de Sherbrooke - Niche regulation of muscle stem cell specification Dr Bentzinger’s group studies the role of regulatory signals in the microenvironment where skeletal muscle stem cells (MuSCs) reside. Understanding how this so-called “stem cell niche” controls MuSCs and how these instructive mechanisms become disrupted in aging and disease, could help - [Julien van Grevenynghe, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/julien-van-grevenynghe-phd/) - Department of Infectious diseases, immunity, cancer and epidemiology, INRS – Institut Armand-Frappier and the Université du Québec Autophagy regulates CD8 T-cell killing activity during chronic HIV-1 infection Autophagy, a natural self-destructive process in cells, eliminates some viruses from cells, and also plays a role in shaping functions of T cells, a primary part of the - [Adena Scheer, MD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/adena-scheer-md/) - Department of Surgery, St Michael’s Hospital, Li Ka Shing Knowledge Institute, and the University of Toronto Cross-cultural communications in breast cancer treatment Among minorities, disparities in breast cancer treatments have been demonstrated across the developed world and have been associated with worse cancer outcomes. In Canada we have the highest rate of foreign-born individuals among - [Catherine Larochelle, MD PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/catherine-larochelle-md-phd/) - CRCHUM, Department of Neurosciences, Universite de Montreal - Molecular mechanisms underlying T lymphocytes interactions with oligodendrocytes in neuroinflammation In multiple sclerosis (MS), there is an abnormal response of immune cells against cells of the brain and spinal cord. Oligodendrocytes, the myelin-producing cells that support and insulate neurons, are injured by the inflammatory response, leaving neurons - [Robert Huber, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/robert-huber-phd/) - Department of Biology, Trent University - Using the social amoeba Dictyostelium discoideum to study Batten disease Mutations in CLN5 cause late-infantile, juvenile, and adults forms of neuronal ceroid lipofuscinosis (NCL), commonly known as Batten disease. This devastating neurological disorder, which is linked to mutations in 13 genetically distinct genes, affects all ages and ethnicities and - [Kyle Biggar, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/kyle-biggar-phd/) - Department of Biology, Carleton University - Identification of new substrates of the histone methyltransferase enzyme, SMYD3, and their implication in lung cancer development Lysine methylation plays a critical role in the development of many human diseases. These small chemical protein modifications allow cells to exert greater control over protein function. Importantly, proteins that control this - [Dylan Cooke, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/dylan-cooke-phd/) - Department of Biomedical Physiology and Kinesiology, Simon Fraser University - Accelerated mapping of individual variation in brain organization with online detection of EMG activity Individuality is widely celebrated in human culture but rarely studied in the laboratory. As with dexterity and athletic coordination, brain organization varies significantly between individuals, though it is not known whether - [Nomazulu Dlamini, MD PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/nomazulu-dlamini-md-phd/) - Division of Neurology, The Hospital for Sick Children - Studying neural network reorganization in dystonia after childhood basal ganglia stroke Dystonia is a disabling and often painful disorder characterized by involuntary, repetitive muscle contractions, twisting movements and abnormal posturing. It is often resistant to treatment, and many children with dystonia develop fixed deformities with significant - [Ian Rodrigue-Gervais, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/ian-rodrigue-gervais-phd/) - Department of Infectious Diseases, INRS - Institut Armand-Frappier - Examining the function of mitochondrial proteases in flu pathogenesis Every year, people fall ill with the flu, a respiratory disease caused by the influenza virus. Our main tools for fighting deadly flu outbreaks are vaccines and antiviral drugs. But, despite their availability in Canada, seasonal flu - [Rebecca Shapiro, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/rebecca-shapiro-phd/) - Department of Molecular and Cellular Biology, University of Guelph - Using genetic and functional genomic analysis to study antifungal drug resistance in Candida auris Combating infectious disease pathogens is a pressing global health challenge. Due to limited treatment options, fungal pathogens pose a unique challenge, and are emerging as a leading cause of human mortality. - [John Trant, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/john-trant-phd/) - Department of Chemistry and Biochemistry, University of Windsor - Developing enzymatically-resistant carbohydrate vaccines for treating lung cancer Therapeutic vaccines incorporating sugar molecules could provide new cancer treatments. Because over 85% of carcinoma cancer cells, regardless of organ, display the same few sugars on their surface, sugars not found on healthy cells, these sugars are promising - [Ali Abdul-Sater, PhD](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/ali-abdul-sater/) - School of Kinesiology and Health Science, York University - Dissecting the role of TRAF1 in regulating inflammatory and autoimmune diseases Autoimmune diseases like Rheumatoid Arthritis (RA) are largely driven by abnormal inflammatory responses. Recent research from Dr Abdul-Sater’s group showed that TRAF1, an immune signaling molecule associated with increased risk to RA, can control inflammation. - [Catharine Whiteside](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/catharine-whiteside/) - Emerita Professor and Former Dean of Medicine, University of Toronto - [William E. Hewitt](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/william-e-hewitt/) - Independent Financial and Investment Consultant - [Avrum I. Gotlieb](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/avrum-i-gotlieb/) - Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto - [Aubie Angel](https://www.bantingdiscoveryfoundation.ca/xt_volanteers/aubie-angel/) - Professor Emeritus, Senior Fellow Massey College, University of Toronto, President Friends of CIHR ## Projects - [Pure water to drink](https://www.bantingdiscoveryfoundation.ca/xt_project/3942/) - Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec odio. Quisque volutpat mattis eros. Nullam malesuada erat ut turpis. Suspendisse urna nibh, viverra non, semper suscipit, posuere a, pede. Donec nec justo eget felis facilisis fermentum. Aliquam porttitor mauris sit amet orci. Aenean dignissim pellentesque felis. Morbi in sem quis dui placerat ornare. Pellentesque odio - [All the children needs proper education](https://www.bantingdiscoveryfoundation.ca/xt_project/3941/) - Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec odio. Quisque volutpat mattis eros. Nullam malesuada erat ut turpis. Suspendisse urna nibh, viverra non, semper suscipit, posuere a, pede. Donec nec justo eget felis facilisis fermentum. Aliquam porttitor mauris sit amet orci. Aenean dignissim pellentesque felis. Morbi in sem quis dui placerat ornare. Pellentesque odio - [Rohingya muslims needs basic humanity](https://www.bantingdiscoveryfoundation.ca/xt_project/3940/) - Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec odio. Quisque volutpat mattis eros. Nullam malesuada erat ut turpis. Suspendisse urna nibh, viverra non, semper suscipit, posuere a, pede. Donec nec justo eget felis facilisis fermentum. Aliquam porttitor mauris sit amet orci. Aenean dignissim pellentesque felis. Morbi in sem quis dui placerat ornare. 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Pellentesque odio - [For children in South Sudan](https://www.bantingdiscoveryfoundation.ca/xt_project/for-children-in-south-sudan/) - Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec odio. Quisque volutpat mattis eros. Nullam malesuada erat ut turpis. Suspendisse urna nibh, viverra non, semper suscipit, posuere a, pede. Donec nec justo eget felis facilisis fermentum. Aliquam porttitor mauris sit amet orci. Aenean dignissim pellentesque felis. Morbi in sem quis dui placerat ornare. Pellentesque odio - [What Inspires Us to Do This?](https://www.bantingdiscoveryfoundation.ca/xt_project/what-inspires-us-to-do-this/) - Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec odio. Quisque volutpat mattis eros. Nullam malesuada erat ut turpis. Suspendisse urna nibh, viverra non, semper suscipit, posuere a, pede. Donec nec justo eget felis facilisis fermentum. Aliquam porttitor mauris sit amet orci. Aenean dignissim pellentesque felis. Morbi in sem quis dui placerat ornare. Pellentesque odio - [New Hunger Relief Program](https://www.bantingdiscoveryfoundation.ca/xt_project/new-hunger-relief-program/) - Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec odio. Quisque volutpat mattis eros. Nullam malesuada erat ut turpis. Suspendisse urna nibh, viverra non, semper suscipit, posuere a, pede. Donec nec justo eget felis facilisis fermentum. Aliquam porttitor mauris sit amet orci. Aenean dignissim pellentesque felis. Morbi in sem quis dui placerat ornare. 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